Recent advances in niacin and lipid metabolism

This review focuses on the current understanding of the physiological mechanisms of action of niacin on lipid metabolism and atherosclerosis. Emerging findings indicate that niacin decreases hepatic triglyceride synthesis and subsequent VLDL/LDL secretion by directly and noncompetitively inhibiting...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Current opinion in lipidology 2013-06, Vol.24 (3), p.239-245
Hauptverfasser:	Kamanna, Vaijinath S., Ganji, Shobha H., Kashyap, Moti L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apolipoprotein A-I - genetics Apolipoprotein A-I - metabolism Atherosclerosis - metabolism Atherosclerosis - pathology Atherosclerosis - prevention & control Cholesterol, HDL - agonists Cholesterol, HDL - metabolism Cholesterol, LDL - antagonists & inhibitors Cholesterol, LDL - metabolism Cholesterol, VLDL - antagonists & inhibitors Cholesterol, VLDL - metabolism Diacylglycerol O-Acyltransferase - genetics Diacylglycerol O-Acyltransferase - metabolism Gene Expression Regulation - drug effects Humans Hypolipidemic Agents - therapeutic use Lipid Metabolism - drug effects Mice Mitochondrial Proton-Translocating ATPases - genetics Mitochondrial Proton-Translocating ATPases - metabolism Niacin - therapeutic use Receptors, G-Protein-Coupled - genetics Receptors, G-Protein-Coupled - metabolism Receptors, Nicotinic - genetics Receptors, Nicotinic - metabolism Triglycerides - antagonists & inhibitors Triglycerides - biosynthesis
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!