Ascorbic Acid Reduces Noise-Induced Nitric Oxide Production in the Guinea Pig Ear

Objectives: Noise‐induced hearing loss can be caused, among other causes, by increased nitric oxide (NO) production in the inner ear leading to nitroactive stress and cell destruction. Some studies in the literature suggest that the degree of hearing loss (HL) could be reduced in an animal model thr...

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Veröffentlicht in:	The Laryngoscope 2008-05, Vol.118 (5), p.837-842
Hauptverfasser:	Heinrich, Ulf-Rüdiger, Fischer, Ilka, Brieger, Jürgen, Rümelin, Andreas, Schmidtmann, Irene, Li, Huige, Mann, Wolf J., Helling, Kai
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals ascorbic acid Ascorbic Acid - blood Ascorbic Acid - pharmacology Biological and medical sciences Cochlea - metabolism Ear, Inner - metabolism Evoked Potentials, Auditory Guinea Pigs hearing threshold inner ear Male Medical sciences Nitric oxide Nitric Oxide - antagonists & inhibitors Nitric Oxide - biosynthesis Noise - adverse effects Organ of Corti - metabolism Otorhinolaryngology. Stomatology Prospective Studies Random Allocation
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