Comparative effectiveness of antiviral treatment for hepatitis B: a systematic review and Bayesian network meta-analysis

OBJECTIVEA wide variety of competing drugs are available to patients for the treatment of chronic hepatitis B. We update a recent meta-analysis to include additional trial evidence with the aim of determining which treatment is the most effective. METHODSTwelve monotherapy or combination therapy wer...

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Veröffentlicht in:	European journal of gastroenterology & hepatology 2015-08, Vol.27 (8), p.882-894
Hauptverfasser:	Govan, Lindsay, Wu, Olivia, Xin, Yiqiao, Hutchinson, Sharon J, Hawkins, Neil
Format:	Artikel
Sprache:	eng
Schlagworte:	Antiviral Agents - adverse effects Antiviral Agents - economics Antiviral Agents - therapeutic use Bayes Theorem Biomarkers - blood Cost-Benefit Analysis DNA, Viral - blood Drug Costs Drug Therapy, Combination Hepatitis B e Antigens - blood Hepatitis B virus - drug effects Hepatitis B virus - genetics Hepatitis B virus - immunology Hepatitis B, Chronic - diagnosis Hepatitis B, Chronic - drug therapy Hepatitis B, Chronic - economics Humans Markov Chains Monte Carlo Method Odds Ratio Time Factors Treatment Outcome Viral Load
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