The fibrinolytic mechanism of defibrotide: effect of defibrotide on plasmin activity

Fibrinolytic activity has been shown to be reduced in many vascular diseases, including hepatic veno-occlusive disease after stem cell transplantation, a microangiopathy characterized by sinusoidal endothelial cell injury. Defibrotide is a polydisperse oligonucleotide with antithrombotic, profibrino...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Blood coagulation & fibrinolysis 2009-12, Vol.20 (8), p.627-634
Hauptverfasser:	Echart, Cinara L, Graziadio, Barbara, Somaini, Simona, Ferro, Laura I, Richardson, Paul G, Fareed, Jawed, Iacobelli, Massimo
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Blood coagulation. Blood cells Dose-Response Relationship, Drug Fibrinogen - metabolism Fibrinolysin - drug effects Fibrinolysis - drug effects Fibrinolytic Agents - pharmacology Fundamental and applied biological sciences. Psychology Hematologic and hematopoietic diseases Hepatic Veno-Occlusive Disease - drug therapy Humans Medical sciences Molecular and cellular biology Plasminogen - metabolism Platelet diseases and coagulopathies Polydeoxyribonucleotides - pharmacology Thrombin - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!