Subtyping of Undifferentiated Non-small Cell Carcinomas in Bronchial Biopsy Specimens

The emergence of treatments for non-small cell lung carcinoma (NSCLC) with differential efficacy and toxicity between subtypes has highlighted the importance of specific pathologic NSCLC subtyping. Most NSCLCs are inoperable, and pathologic diagnosis is made only on small tissue samples that are pro...

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Veröffentlicht in:	Journal of thoracic oncology 2010-04, Vol.5 (4), p.442-447
Hauptverfasser:	Loo, Peh Sun, Thomas, Stuart C., Nicolson, Marianne C., Fyfe, Margaret N., Kerr, Keith M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - classification Adenocarcinoma - metabolism Adenocarcinoma - pathology Biomarkers, Tumor - metabolism Biopsy, Fine-Needle Bronchi - metabolism Bronchi - pathology Bronchial biopsy diagnosis Carcinoma, Large Cell - classification Carcinoma, Large Cell - metabolism Carcinoma, Large Cell - pathology Carcinoma, Non-Small-Cell Lung - classification Carcinoma, Non-Small-Cell Lung - metabolism Carcinoma, Non-Small-Cell Lung - pathology Carcinoma, Squamous Cell - classification Carcinoma, Squamous Cell - metabolism Carcinoma, Squamous Cell - pathology Cell Differentiation Humans Immunoenzyme Techniques Immunohistochemistry Keratin-5 - metabolism Keratin-6 - metabolism Lung Neoplasms - classification Lung Neoplasms - metabolism Lung Neoplasms - pathology Mucins - metabolism Neoplasm Staging Non-small cell lung carcinoma NSCLC subtype NSCLC-NOS Nuclear Proteins - metabolism p63 Predictive value Prognosis Prospective Studies S100 Calcium Binding Protein A7 S100 Proteins - metabolism Sensitivity and Specificity Survival Rate Thyroid Nuclear Factor 1 Trans-Activators - metabolism Transcription Factors - metabolism TTF1 Tumor Suppressor Proteins - metabolism Undifferentiated carcinoma
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