Drug Resistance in Human Immunodeficiency Virus Type-1 Infected Zambian Children Using Adult Fixed Dose Combination Stavudine, Lamivudine, and Nevirapine

BACKGROUND:There are few medium-term virologic data in children from resource-limited settings taking adult fixed-dose-combination antiretroviral therapy (cART) without viral load monitoring. METHODS:CHAP2 (Children with HIV Antibiotic Prophylaxis 2) is a prospective cohort of Zambian children using...

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Veröffentlicht in:	The Pediatric infectious disease journal 2010-08, Vol.29 (8), p.e57-e62
Hauptverfasser:	Gupta, Ravindra K, Ford, Deborah, Mulenga, Veronica, Walker, A Sarah, Kabamba, Desire, Kalumbi, Moxmalama, Grant, Paul R, Ferrier, Alexander, Pillay, Deenan, Gibb, Diana M, Chintu, Chifumbe
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Substitution - genetics Anti-HIV Agents - administration & dosage Anti-HIV Agents - pharmacology CD4 Lymphocyte Count Child Child, Preschool Cohort Studies Drug Monitoring Drug Resistance, Viral Female Follow-Up Studies HIV Infections - drug therapy HIV Infections - virology HIV-1 - drug effects HIV-1 - isolation & purification Humans Lamivudine - administration & dosage Lamivudine - pharmacology Male Mutation, Missense Nevirapine - administration & dosage Nevirapine - pharmacology Prospective Studies Stavudine - administration & dosage Stavudine - pharmacology Treatment Failure Viral Load Viral Proteins - genetics Zambia
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