A COMT gene haplotype associated with methamphetamine abuse

INTRODUCTIONMethamphetamine (MAMP) use is highly associated with psychiatric disorders with 12–13% of MAMP-dependent patients experiencing psychotic symptoms. Substance abuse and dependence may primarily involve the mesolimbic pathway and dopaminergic brain structures. It follows that dopaminergic g...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Pharmacogenetics and genomics 2011-11, Vol.21 (11), p.731-740
Hauptverfasser:	Jugurnauth, Sarah K, Chen, Chih-Ken, Barnes, Michael R, Li, Tao, Lin, Shih-Ku, Liu, Hsing-Cheng, Collier, David A, Breen, Gerome
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Armadillo Domain Proteins - genetics Biological and medical sciences Catechol O-Methyltransferase - genetics Child Computational Biology DiGeorge Syndrome - enzymology DiGeorge Syndrome - genetics Enzyme Assays Female Gene Expression Regulation, Enzymologic General pharmacology Genetic Predisposition to Disease Haplotypes - genetics Humans Luciferases - metabolism Male Medical sciences Methamphetamine - adverse effects Middle Aged Pharmacokinetics. Pharmacogenetics. Drug-receptor interactions Pharmacology. Drug treatments Polymorphism, Single Nucleotide - genetics RNA, Messenger - genetics RNA, Messenger - metabolism Substance-Related Disorders - enzymology Substance-Related Disorders - genetics Young Adult
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!