Poly-l-Lactic Acid for Gluteal Augmentation found to be Safe and Effective in Retrospective Clinical Review of 60 Patients
Poly-L-lactic acid (PLLA) is a well-established biostimulator that induces neocollagenesis, allowing for volume loss correction. Although PLLA is FDA approved to treat mid-to-lower facial wrinkling, it has grown increasingly popular as a nonsurgical, minimally invasive procedure for soft-tissue volu...
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Veröffentlicht in: | Dermatologic surgery 2020-10, Vol.46 (Suppl 1), p.S46-S53 |
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creator | Durairaj, Kalpna K. Devgan, Lara Lee, BS, Alexandria Khachatourian, BS, Nooneh Nguyen, BS, Vivian Issa, BS, Thomas Baker, Omer |
description | Poly-L-lactic acid (PLLA) is a well-established biostimulator that induces neocollagenesis, allowing for volume loss correction. Although PLLA is FDA approved to treat mid-to-lower facial wrinkling, it has grown increasingly popular as a nonsurgical, minimally invasive procedure for soft-tissue volume augmentation of other extremities. However, research detailing PLLA buttock injections is still lacking.
The purpose of this study is to determine the safety and efficacy of PLLA for buttock augmentation.
A clinical retrospective review of 60 patients (ages 23-54 years) were followed for 2 years by 2 investigators. Patients underwent 1 to 3 treatments, spaced 4 to 6 weeks apart, and received 2 to 12 vials per session (based on the patient budget). Pretreatment and post-treatment photographs were assessed by the primary and secondary investigator in blinded and double-blinded surveys, respectively. The Global Aesthetic Improvement Scale was used to quantify improvements in volume, skin texture, and cellulite dimpling.
Poly-L-lactic acid allows for visible volume amplification, improved skin texture, and softened cellulite dimpling in the buttocks when at least 20 vials are used.
Poly-L-lactic acid is safe and effective for overall aesthetic enhancement of the buttocks if used in adequate quantity (minimum 20 vials) for all women, independent of age or the number of sessions. |
doi_str_mv | 10.1097/DSS.0000000000002598 |
format | Article |
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The purpose of this study is to determine the safety and efficacy of PLLA for buttock augmentation.
A clinical retrospective review of 60 patients (ages 23-54 years) were followed for 2 years by 2 investigators. Patients underwent 1 to 3 treatments, spaced 4 to 6 weeks apart, and received 2 to 12 vials per session (based on the patient budget). Pretreatment and post-treatment photographs were assessed by the primary and secondary investigator in blinded and double-blinded surveys, respectively. The Global Aesthetic Improvement Scale was used to quantify improvements in volume, skin texture, and cellulite dimpling.
Poly-L-lactic acid allows for visible volume amplification, improved skin texture, and softened cellulite dimpling in the buttocks when at least 20 vials are used.
Poly-L-lactic acid is safe and effective for overall aesthetic enhancement of the buttocks if used in adequate quantity (minimum 20 vials) for all women, independent of age or the number of sessions.</description><identifier>ISSN: 1076-0512</identifier><identifier>EISSN: 1524-4725</identifier><identifier>DOI: 10.1097/DSS.0000000000002598</identifier><identifier>PMID: 32976171</identifier><language>eng</language><publisher>United States: Lippincott Williams & Wilkins</publisher><subject>Adult ; Body Contouring - adverse effects ; Body Contouring - methods ; Body Mass Index ; Buttocks - anatomy & histology ; Dermal Fillers - administration & dosage ; Dermal Fillers - adverse effects ; Drug Administration Schedule ; Female ; Follow-Up Studies ; Humans ; Middle Aged ; Off-Label Use ; Polyesters - administration & dosage ; Polyesters - adverse effects ; Retrospective Studies ; Skin Aging - drug effects ; Treatment Outcome ; Young Adult</subject><ispartof>Dermatologic surgery, 2020-10, Vol.46 (Suppl 1), p.S46-S53</ispartof><rights>Lippincott Williams & Wilkins</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3529-f65671e969e9091bef55da6a94ff070d175a38025d1cd6c16bd0567bce8a79e33</citedby><cites>FETCH-LOGICAL-c3529-f65671e969e9091bef55da6a94ff070d175a38025d1cd6c16bd0567bce8a79e33</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32976171$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Durairaj, Kalpna K.</creatorcontrib><creatorcontrib>Devgan, Lara</creatorcontrib><creatorcontrib>Lee, BS, Alexandria</creatorcontrib><creatorcontrib>Khachatourian, BS, Nooneh</creatorcontrib><creatorcontrib>Nguyen, BS, Vivian</creatorcontrib><creatorcontrib>Issa, BS, Thomas</creatorcontrib><creatorcontrib>Baker, Omer</creatorcontrib><title>Poly-l-Lactic Acid for Gluteal Augmentation found to be Safe and Effective in Retrospective Clinical Review of 60 Patients</title><title>Dermatologic surgery</title><addtitle>Dermatol Surg</addtitle><description>Poly-L-lactic acid (PLLA) is a well-established biostimulator that induces neocollagenesis, allowing for volume loss correction. Although PLLA is FDA approved to treat mid-to-lower facial wrinkling, it has grown increasingly popular as a nonsurgical, minimally invasive procedure for soft-tissue volume augmentation of other extremities. However, research detailing PLLA buttock injections is still lacking.
The purpose of this study is to determine the safety and efficacy of PLLA for buttock augmentation.
A clinical retrospective review of 60 patients (ages 23-54 years) were followed for 2 years by 2 investigators. Patients underwent 1 to 3 treatments, spaced 4 to 6 weeks apart, and received 2 to 12 vials per session (based on the patient budget). Pretreatment and post-treatment photographs were assessed by the primary and secondary investigator in blinded and double-blinded surveys, respectively. The Global Aesthetic Improvement Scale was used to quantify improvements in volume, skin texture, and cellulite dimpling.
Poly-L-lactic acid allows for visible volume amplification, improved skin texture, and softened cellulite dimpling in the buttocks when at least 20 vials are used.
Poly-L-lactic acid is safe and effective for overall aesthetic enhancement of the buttocks if used in adequate quantity (minimum 20 vials) for all women, independent of age or the number of sessions.</description><subject>Adult</subject><subject>Body Contouring - adverse effects</subject><subject>Body Contouring - methods</subject><subject>Body Mass Index</subject><subject>Buttocks - anatomy & histology</subject><subject>Dermal Fillers - administration & dosage</subject><subject>Dermal Fillers - adverse effects</subject><subject>Drug Administration Schedule</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Humans</subject><subject>Middle Aged</subject><subject>Off-Label Use</subject><subject>Polyesters - administration & dosage</subject><subject>Polyesters - adverse effects</subject><subject>Retrospective Studies</subject><subject>Skin Aging - drug effects</subject><subject>Treatment Outcome</subject><subject>Young Adult</subject><issn>1076-0512</issn><issn>1524-4725</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdkNtOAjEQhhujEUXfwJi-QLHtbtvtJUFEExIJ6PWm251Kddkle4Dg01sCHmJvpjPN92X6I3TD6IBRre7uF4sB_XO40MkJumCCxyRWXJyGO1WSUMF4D102zTuljOuInqNexLWSTLEL9Dmrih0pyNTY1ls8tD7HrqrxpOhaMAUedm8rKFvT-qoMD12Z47bCGeCFcYBNaMfOQWA3gH2J59DWVbM-DkaFL70NljlsPGxx5bCkeBZkQdlcoTNnigauj7WPXh_GL6NHMn2ePI2GU2IjwTVxUkjFQEsNmmqWgRMiN9Lo2DmqaM6UMFESvp8zm0vLZJbTQGQWEqM0RFEfxQevDas1Nbh0XfuVqXcpo-k-yjREmf6PMmC3B2zdZSvIf6Dv7H6926pooW4-im4LdboMsbXLvS_miieEU05Z6BjZq3X0BXksfpA</recordid><startdate>20201001</startdate><enddate>20201001</enddate><creator>Durairaj, Kalpna K.</creator><creator>Devgan, Lara</creator><creator>Lee, BS, Alexandria</creator><creator>Khachatourian, BS, Nooneh</creator><creator>Nguyen, BS, Vivian</creator><creator>Issa, BS, Thomas</creator><creator>Baker, Omer</creator><general>Lippincott Williams & Wilkins</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>20201001</creationdate><title>Poly-l-Lactic Acid for Gluteal Augmentation found to be Safe and Effective in Retrospective Clinical Review of 60 Patients</title><author>Durairaj, Kalpna K. ; Devgan, Lara ; Lee, BS, Alexandria ; Khachatourian, BS, Nooneh ; Nguyen, BS, Vivian ; Issa, BS, Thomas ; Baker, Omer</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3529-f65671e969e9091bef55da6a94ff070d175a38025d1cd6c16bd0567bce8a79e33</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Adult</topic><topic>Body Contouring - adverse effects</topic><topic>Body Contouring - methods</topic><topic>Body Mass Index</topic><topic>Buttocks - anatomy & histology</topic><topic>Dermal Fillers - administration & dosage</topic><topic>Dermal Fillers - adverse effects</topic><topic>Drug Administration Schedule</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Humans</topic><topic>Middle Aged</topic><topic>Off-Label Use</topic><topic>Polyesters - administration & dosage</topic><topic>Polyesters - adverse effects</topic><topic>Retrospective Studies</topic><topic>Skin Aging - drug effects</topic><topic>Treatment Outcome</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Durairaj, Kalpna K.</creatorcontrib><creatorcontrib>Devgan, Lara</creatorcontrib><creatorcontrib>Lee, BS, Alexandria</creatorcontrib><creatorcontrib>Khachatourian, BS, Nooneh</creatorcontrib><creatorcontrib>Nguyen, BS, Vivian</creatorcontrib><creatorcontrib>Issa, BS, Thomas</creatorcontrib><creatorcontrib>Baker, Omer</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><jtitle>Dermatologic surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Durairaj, Kalpna K.</au><au>Devgan, Lara</au><au>Lee, BS, Alexandria</au><au>Khachatourian, BS, Nooneh</au><au>Nguyen, BS, Vivian</au><au>Issa, BS, Thomas</au><au>Baker, Omer</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Poly-l-Lactic Acid for Gluteal Augmentation found to be Safe and Effective in Retrospective Clinical Review of 60 Patients</atitle><jtitle>Dermatologic surgery</jtitle><addtitle>Dermatol Surg</addtitle><date>2020-10-01</date><risdate>2020</risdate><volume>46</volume><issue>Suppl 1</issue><spage>S46</spage><epage>S53</epage><pages>S46-S53</pages><issn>1076-0512</issn><eissn>1524-4725</eissn><abstract>Poly-L-lactic acid (PLLA) is a well-established biostimulator that induces neocollagenesis, allowing for volume loss correction. Although PLLA is FDA approved to treat mid-to-lower facial wrinkling, it has grown increasingly popular as a nonsurgical, minimally invasive procedure for soft-tissue volume augmentation of other extremities. However, research detailing PLLA buttock injections is still lacking.
The purpose of this study is to determine the safety and efficacy of PLLA for buttock augmentation.
A clinical retrospective review of 60 patients (ages 23-54 years) were followed for 2 years by 2 investigators. Patients underwent 1 to 3 treatments, spaced 4 to 6 weeks apart, and received 2 to 12 vials per session (based on the patient budget). Pretreatment and post-treatment photographs were assessed by the primary and secondary investigator in blinded and double-blinded surveys, respectively. The Global Aesthetic Improvement Scale was used to quantify improvements in volume, skin texture, and cellulite dimpling.
Poly-L-lactic acid allows for visible volume amplification, improved skin texture, and softened cellulite dimpling in the buttocks when at least 20 vials are used.
Poly-L-lactic acid is safe and effective for overall aesthetic enhancement of the buttocks if used in adequate quantity (minimum 20 vials) for all women, independent of age or the number of sessions.</abstract><cop>United States</cop><pub>Lippincott Williams & Wilkins</pub><pmid>32976171</pmid><doi>10.1097/DSS.0000000000002598</doi></addata></record> |
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subjects | Adult Body Contouring - adverse effects Body Contouring - methods Body Mass Index Buttocks - anatomy & histology Dermal Fillers - administration & dosage Dermal Fillers - adverse effects Drug Administration Schedule Female Follow-Up Studies Humans Middle Aged Off-Label Use Polyesters - administration & dosage Polyesters - adverse effects Retrospective Studies Skin Aging - drug effects Treatment Outcome Young Adult |
title | Poly-l-Lactic Acid for Gluteal Augmentation found to be Safe and Effective in Retrospective Clinical Review of 60 Patients |
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