Successful desensitization to oxaliplatin with incorporation of calcium gluconate and magnesium sulfate

Since the results of the MOSAIC trial demonstrated an improved disease-free survival in stage III colorectal patients treated with oxaliplatin combined with 5-fluorouracil and folinic acid when they were compared with those treated with 5-fluorouracil and folinic acid alone, the addition of this org...

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Veröffentlicht in:	Anti-cancer drugs 2007-07, Vol.18 (6), p.721-724
Hauptverfasser:	Wrzesinski, Stephen H, McGurk, Meghan L, Donovan, Constance T, Ferencz, Thomas M, Saif, Muhammad Wasif
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - drug therapy Adenocarcinoma - pathology Adult Antineoplastic Combined Chemotherapy Protocols - administration & dosage Antineoplastic Combined Chemotherapy Protocols - adverse effects Antineoplastic Combined Chemotherapy Protocols - therapeutic use Calcium Gluconate - administration & dosage Calcium Gluconate - therapeutic use Drug Hypersensitivity - prevention & control Female Fluorouracil - administration & dosage Fluorouracil - adverse effects Fluorouracil - therapeutic use Humans Leucovorin - administration & dosage Leucovorin - adverse effects Leucovorin - therapeutic use Magnesium Sulfate - administration & dosage Magnesium Sulfate - therapeutic use Neoplasm Staging Organoplatinum Compounds - administration & dosage Organoplatinum Compounds - adverse effects Organoplatinum Compounds - therapeutic use Sigmoid Neoplasms - drug therapy Sigmoid Neoplasms - pathology Treatment Outcome
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