Ketamine and Midazolam Delivered by Patient-controlled Analgesia in Relieving Pain Associated With Burns Dressings
BACKGROUNDA study involving the use of a mixture of ketamine and midazolam delivered via patient-controlled analgesia (PCA) device was trialed to assess its effectiveness in reducing pain associated with repeated burns dressings in an adult population. METHODSPatients undergoing burns dressings chan...
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| Veröffentlicht in: | The Clinical journal of pain 2008-09, Vol.24 (7), p.568-571 |
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| creator | MacPherson, Ross D Woods, David Penfold, Joanna |
| description | BACKGROUNDA study involving the use of a mixture of ketamine and midazolam delivered via patient-controlled analgesia (PCA) device was trialed to assess its effectiveness in reducing pain associated with repeated burns dressings in an adult population.
METHODSPatients undergoing burns dressings changes were given a PCA device of ketamine and midazolam to use during the procedure. The aims were to investigate the efficacy of the device and to ascertain what (if any) adverse effects were associated with its use.
RESULTSDuring the trial period, 44 patients who underwent 95 separate procedures were enrolled. The effectiveness of the device was rated (out of 10) by both staff and patients with the mean scores being 8.47 and 8.50, respectively. In all but 1 case, the proposed procedure was carried out successfully. Thirteen patients reported a total of 23 adverse effects, with hallucinations (11) being the most common.
CONCLUSIONSThe use of ketamine/midazolam delivered by PCA was shown to be an effective means of pain control during burns dressings as assessed by both staff and patients. The incidence of adverse events was low. |
| doi_str_mv | 10.1097/AJP.0b013e31816cdb20 |
| format | Article |
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METHODSPatients undergoing burns dressings changes were given a PCA device of ketamine and midazolam to use during the procedure. The aims were to investigate the efficacy of the device and to ascertain what (if any) adverse effects were associated with its use.
RESULTSDuring the trial period, 44 patients who underwent 95 separate procedures were enrolled. The effectiveness of the device was rated (out of 10) by both staff and patients with the mean scores being 8.47 and 8.50, respectively. In all but 1 case, the proposed procedure was carried out successfully. Thirteen patients reported a total of 23 adverse effects, with hallucinations (11) being the most common.
CONCLUSIONSThe use of ketamine/midazolam delivered by PCA was shown to be an effective means of pain control during burns dressings as assessed by both staff and patients. The incidence of adverse events was low.</description><identifier>ISSN: 0749-8047</identifier><identifier>EISSN: 1536-5409</identifier><identifier>DOI: 10.1097/AJP.0b013e31816cdb20</identifier><identifier>PMID: 18716494</identifier><identifier>CODEN: CJPAEU</identifier><language>eng</language><publisher>Hagerstown, MD: Lippincott Williams & Wilkins, Inc</publisher><subject>Adolescent ; Adult ; Aged ; Analgesia, Patient-Controlled - methods ; Analgesics - administration & dosage ; Analgesics - adverse effects ; Bandages - adverse effects ; Biological and medical sciences ; Burns - complications ; Burns - therapy ; Drug Therapy, Combination ; Female ; Fundamental and applied biological sciences. Psychology ; Humans ; Hypnotics and Sedatives - administration & dosage ; Hypnotics and Sedatives - adverse effects ; Ketamine - administration & dosage ; Ketamine - adverse effects ; Male ; Medical sciences ; Midazolam - administration & dosage ; Midazolam - adverse effects ; Middle Aged ; Multiple sclerosis and variants. Guillain barré syndrome and other inflammatory polyneuropathies. Leukoencephalitis ; Neurology ; Pain - etiology ; Pain - prevention & control ; Pain Measurement - drug effects ; Somesthesis and somesthetic pathways (proprioception, exteroception, nociception); interoception; electrolocation. Sensory receptors ; Treatment Outcome ; Vertebrates: nervous system and sense organs</subject><ispartof>The Clinical journal of pain, 2008-09, Vol.24 (7), p.568-571</ispartof><rights>2008 Lippincott Williams & Wilkins, Inc.</rights><rights>2008 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3802-c648e83b827faef3b2f3a829092816b96296beef377b630e4af1b32912bcf3203</citedby><cites>FETCH-LOGICAL-c3802-c648e83b827faef3b2f3a829092816b96296beef377b630e4af1b32912bcf3203</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=20607838$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18716494$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>MacPherson, Ross D</creatorcontrib><creatorcontrib>Woods, David</creatorcontrib><creatorcontrib>Penfold, Joanna</creatorcontrib><title>Ketamine and Midazolam Delivered by Patient-controlled Analgesia in Relieving Pain Associated With Burns Dressings</title><title>The Clinical journal of pain</title><addtitle>Clin J Pain</addtitle><description>BACKGROUNDA study involving the use of a mixture of ketamine and midazolam delivered via patient-controlled analgesia (PCA) device was trialed to assess its effectiveness in reducing pain associated with repeated burns dressings in an adult population.
METHODSPatients undergoing burns dressings changes were given a PCA device of ketamine and midazolam to use during the procedure. The aims were to investigate the efficacy of the device and to ascertain what (if any) adverse effects were associated with its use.
RESULTSDuring the trial period, 44 patients who underwent 95 separate procedures were enrolled. The effectiveness of the device was rated (out of 10) by both staff and patients with the mean scores being 8.47 and 8.50, respectively. In all but 1 case, the proposed procedure was carried out successfully. Thirteen patients reported a total of 23 adverse effects, with hallucinations (11) being the most common.
CONCLUSIONSThe use of ketamine/midazolam delivered by PCA was shown to be an effective means of pain control during burns dressings as assessed by both staff and patients. The incidence of adverse events was low.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Analgesia, Patient-Controlled - methods</subject><subject>Analgesics - administration & dosage</subject><subject>Analgesics - adverse effects</subject><subject>Bandages - adverse effects</subject><subject>Biological and medical sciences</subject><subject>Burns - complications</subject><subject>Burns - therapy</subject><subject>Drug Therapy, Combination</subject><subject>Female</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Humans</subject><subject>Hypnotics and Sedatives - administration & dosage</subject><subject>Hypnotics and Sedatives - adverse effects</subject><subject>Ketamine - administration & dosage</subject><subject>Ketamine - adverse effects</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Midazolam - administration & dosage</subject><subject>Midazolam - adverse effects</subject><subject>Middle Aged</subject><subject>Multiple sclerosis and variants. Guillain barré syndrome and other inflammatory polyneuropathies. Leukoencephalitis</subject><subject>Neurology</subject><subject>Pain - etiology</subject><subject>Pain - prevention & control</subject><subject>Pain Measurement - drug effects</subject><subject>Somesthesis and somesthetic pathways (proprioception, exteroception, nociception); interoception; electrolocation. Sensory receptors</subject><subject>Treatment Outcome</subject><subject>Vertebrates: nervous system and sense organs</subject><issn>0749-8047</issn><issn>1536-5409</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdkMFOHDEMhqOqFWwpb1BVufQ44CSzM8lxC7SFgooQiOPIyXjYtNkMSmZB9OkbYAUSvli2v9-Wf8Y-C9gTYNr9xcn5HlgQipTQonG9lfCOzcRcNdW8BvOezaCtTaWhbrfZx5z_AIi51LDFtoVuRVObesbSL5pw5SNxjD0_8z3-GwOu-CEFf0eJem4f-DlOnuJUuTFOaQyhdBcRww1lj9xHflFguvPxppClXOQ8Oo9Twa79tOTf1ilmfpgo58LkT-zDgCHT7ibvsKvvR5cHP6vT3z-ODxanlVMaZOWaWpNWVst2QBqUlYNCLQ0YWd61ppGmsVQGbWsbBVTjIKySRkjrBiVB7bD6ea9LY86Jhu42-RWmh05A92hhVyzs3lpYZF-eZbdru6L-VbTxrABfNwBmh2FIGJ3PL5yEBlqt9Ov9-zFMlPLfsL6n1C0Jw7TsoIScg64kgAZTquqppf4DgliLcw</recordid><startdate>200809</startdate><enddate>200809</enddate><creator>MacPherson, Ross D</creator><creator>Woods, David</creator><creator>Penfold, Joanna</creator><general>Lippincott Williams & Wilkins, Inc</general><general>Lippincott Williams and Wilkins</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>200809</creationdate><title>Ketamine and Midazolam Delivered by Patient-controlled Analgesia in Relieving Pain Associated With Burns Dressings</title><author>MacPherson, Ross D ; Woods, David ; Penfold, Joanna</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3802-c648e83b827faef3b2f3a829092816b96296beef377b630e4af1b32912bcf3203</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Analgesia, Patient-Controlled - methods</topic><topic>Analgesics - administration & dosage</topic><topic>Analgesics - adverse effects</topic><topic>Bandages - adverse effects</topic><topic>Biological and medical sciences</topic><topic>Burns - complications</topic><topic>Burns - therapy</topic><topic>Drug Therapy, Combination</topic><topic>Female</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Humans</topic><topic>Hypnotics and Sedatives - administration & dosage</topic><topic>Hypnotics and Sedatives - adverse effects</topic><topic>Ketamine - administration & dosage</topic><topic>Ketamine - adverse effects</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Midazolam - administration & dosage</topic><topic>Midazolam - adverse effects</topic><topic>Middle Aged</topic><topic>Multiple sclerosis and variants. Guillain barré syndrome and other inflammatory polyneuropathies. Leukoencephalitis</topic><topic>Neurology</topic><topic>Pain - etiology</topic><topic>Pain - prevention & control</topic><topic>Pain Measurement - drug effects</topic><topic>Somesthesis and somesthetic pathways (proprioception, exteroception, nociception); interoception; electrolocation. Sensory receptors</topic><topic>Treatment Outcome</topic><topic>Vertebrates: nervous system and sense organs</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>MacPherson, Ross D</creatorcontrib><creatorcontrib>Woods, David</creatorcontrib><creatorcontrib>Penfold, Joanna</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><jtitle>The Clinical journal of pain</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>MacPherson, Ross D</au><au>Woods, David</au><au>Penfold, Joanna</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Ketamine and Midazolam Delivered by Patient-controlled Analgesia in Relieving Pain Associated With Burns Dressings</atitle><jtitle>The Clinical journal of pain</jtitle><addtitle>Clin J Pain</addtitle><date>2008-09</date><risdate>2008</risdate><volume>24</volume><issue>7</issue><spage>568</spage><epage>571</epage><pages>568-571</pages><issn>0749-8047</issn><eissn>1536-5409</eissn><coden>CJPAEU</coden><abstract>BACKGROUNDA study involving the use of a mixture of ketamine and midazolam delivered via patient-controlled analgesia (PCA) device was trialed to assess its effectiveness in reducing pain associated with repeated burns dressings in an adult population.
METHODSPatients undergoing burns dressings changes were given a PCA device of ketamine and midazolam to use during the procedure. The aims were to investigate the efficacy of the device and to ascertain what (if any) adverse effects were associated with its use.
RESULTSDuring the trial period, 44 patients who underwent 95 separate procedures were enrolled. The effectiveness of the device was rated (out of 10) by both staff and patients with the mean scores being 8.47 and 8.50, respectively. In all but 1 case, the proposed procedure was carried out successfully. Thirteen patients reported a total of 23 adverse effects, with hallucinations (11) being the most common.
CONCLUSIONSThe use of ketamine/midazolam delivered by PCA was shown to be an effective means of pain control during burns dressings as assessed by both staff and patients. The incidence of adverse events was low.</abstract><cop>Hagerstown, MD</cop><pub>Lippincott Williams & Wilkins, Inc</pub><pmid>18716494</pmid><doi>10.1097/AJP.0b013e31816cdb20</doi><tpages>4</tpages></addata></record> |
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| ispartof | The Clinical journal of pain, 2008-09, Vol.24 (7), p.568-571 |
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| source | MEDLINE; Journals@Ovid Complete |
| subjects | Adolescent Adult Aged Analgesia, Patient-Controlled - methods Analgesics - administration & dosage Analgesics - adverse effects Bandages - adverse effects Biological and medical sciences Burns - complications Burns - therapy Drug Therapy, Combination Female Fundamental and applied biological sciences. Psychology Humans Hypnotics and Sedatives - administration & dosage Hypnotics and Sedatives - adverse effects Ketamine - administration & dosage Ketamine - adverse effects Male Medical sciences Midazolam - administration & dosage Midazolam - adverse effects Middle Aged Multiple sclerosis and variants. Guillain barré syndrome and other inflammatory polyneuropathies. Leukoencephalitis Neurology Pain - etiology Pain - prevention & control Pain Measurement - drug effects Somesthesis and somesthetic pathways (proprioception, exteroception, nociception) interoception electrolocation. Sensory receptors Treatment Outcome Vertebrates: nervous system and sense organs |
| title | Ketamine and Midazolam Delivered by Patient-controlled Analgesia in Relieving Pain Associated With Burns Dressings |
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