Hydrocodone/Acetaminophen and Tramadol Chlorhydrate Combination Tablets for the Management of Chronic Cancer Pain: A Double-blind Comparative Trial

OBJETIVESThe purpose of this study was to compare the analgesic efficacy and tolerability of opioids hydrocodone and tramadol in the relief of cancer pain. METHODSOne hundred and eighteen patients with chronic cancer pain participated in a double-blind, randomized controlled trial. Sixty-two patient...

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Veröffentlicht in:	The Clinical journal of pain 2008-01, Vol.24 (1), p.1-4
Hauptverfasser:	Rodriguez, Rene Fernando, Castillo, Javier M, Castillo, María P, Montoya, Olga, Daza, Paola, Rodríguez, Mario F, Restrepo, José M, León, Miguel E, Angel, Ana M
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetaminophen - administration & dosage Acetaminophen - adverse effects Acetaminophen - therapeutic use Aged Analgesics, Non-Narcotic - administration & dosage Analgesics, Non-Narcotic - adverse effects Analgesics, Non-Narcotic - therapeutic use Analgesics, Opioid - administration & dosage Analgesics, Opioid - adverse effects Analgesics, Opioid - therapeutic use Biological and medical sciences Double-Blind Method Drug Combinations Female Fundamental and applied biological sciences. Psychology Humans Hydrocodone - administration & dosage Hydrocodone - adverse effects Hydrocodone - therapeutic use Immunomodulators Male Medical sciences Middle Aged Multiple sclerosis and variants. Guillain barré syndrome and other inflammatory polyneuropathies. Leukoencephalitis Neoplasms - complications Neurology Pain Measurement Pain, Intractable - drug therapy Pain, Intractable - etiology Pharmacology. Drug treatments Somesthesis and somesthetic pathways (proprioception, exteroception, nociception) interoception electrolocation. Sensory receptors Tablets Tramadol - therapeutic use Treatment Outcome Vertebrates: nervous system and sense organs
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