Challenges in the Development of Prescription Opioid Abuse-deterrent Formulations

Opioid analgesics remain the cornerstone of effective management for moderate-to-severe pain. In the face of persistent lack of access to opioids by patients with legitimate pain problems, the rate of prescription opioid abuse in the United States has escalated over the past 15 years. Abuse-deterren...

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Veröffentlicht in:	The Clinical journal of pain 2007-10, Vol.23 (8), p.648-660
Hauptverfasser:	Katz, Nathaniel P, Adams, Edgar H, Chilcoat, Howard, Colucci, Robert D, Comer, Sandra D, Goliber, Philip, Grudzinskas, Charles, Jasinski, Donald, Lande, Stephen D, Passik, Steven D, Schnoll, Sidney H, Sellers, Edward, Travers, Debra, Weiss, Roger
Format:	Artikel
Sprache:	eng
Schlagworte:	Analgesics, Opioid - administration & dosage Analgesics, Opioid - chemistry Analgesics, Opioid - economics Animals Biological and medical sciences Chemistry, Pharmaceutical - economics Development. Senescence. Regeneration. Transplantation Drug Prescriptions Fundamental and applied biological sciences. Psychology Humans Isolated neuron and nerve. Neuroglia Legislation, Drug Medical sciences Neurology Opioid-Related Disorders - epidemiology Opioid-Related Disorders - prevention & control Opioid-Related Disorders - psychology Population Surveillance Research Design Somesthesis and somesthetic pathways (proprioception, exteroception, nociception) interoception electrolocation. Sensory receptors Substance Abuse Detection Terminology as Topic Vertebrates: nervous system and sense organs
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