Protein kinase C inhibitors in the treatment and prevention of diabetic complications

Diabetic complications are known to be associated with activation of the protein kinase C pathway through the de novo synthesis of diacylglycerol. Multiple studies have reported that the activation of protein kinase C leads to increased production of extracellular matrix and cytokines and enhances c...

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Veröffentlicht in:Current opinion in endocrinology & diabetes 2001-08, Vol.8 (4), p.197-204
Hauptverfasser: Gabriele, Annarita, King, George Liang
Format: Artikel
Sprache:eng
Online-Zugang:Volltext
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