Amphetamine withdrawal does not produce a depressive-like state in rats as measured by three behavioral tests

Administration of amphetamine (AMPH) can induce symptoms of psychosis in humans and locomotor sensitization in rats; in contrast, withdrawal from a period of AMPH intake is most often associated with symptoms of human endogenous depression. The aim of this study was to determine whether AMPH withdra...

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Veröffentlicht in:	Behavioural pharmacology 2003-02, Vol.14 (1), p.1-18
Hauptverfasser:	Russig, H, Pezze, M.-A, Nanz-Bahr, N.I, Pryce, C.R, Feldon, J, Murphy, C.A
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenocorticotropic Hormone - blood Amphetamine - administration & dosage Amphetamine - adverse effects Animals Behavior, Animal - drug effects Central Nervous System Stimulants - administration & dosage Central Nervous System Stimulants - adverse effects Corticosterone - blood Depression - chemically induced Depression - psychology Dose-Response Relationship, Drug Helplessness, Learned Male Motor Activity Radioimmunoassay Rats Rats, Wistar Substance Withdrawal Syndrome - psychology
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