Sequence of molecular genetic events in colorectal tumorigenesis

Intensive screening for genetic alteration in colorectal cancer led to the identification of two types of colorectal tumours that are distinct by their carcinogenesis processes. The first group, named LOH (for loss of heterozygosity)-positive, is characterized by hyperploidy and allelic losses invol...

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Veröffentlicht in:	European journal of cancer prevention 1999-12, Vol.8, p.S39-S47
Hauptverfasser:	Laurent-Puig, P, Blons, H, Cugnenc, P-H
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - genetics Colorectal Neoplasms - genetics Female Gene Expression Genes, APC - physiology Genes, p53 - physiology Genes, ras - physiology Genes, Tumor Suppressor - physiology Genetic Predisposition to Disease Humans Male Molecular Biology Mutation Sensitivity and Specificity
Online-Zugang:	Volltext
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