Dual role of oestrogens as hormones and pro–carcinogens: tumour initiation by metabolic activation of oestrogens

Epidemiological evidence increasingly points to exogenous or endogenous oestrogens as a risk factor for breast cancer. However, it is unlikely that induction of oestrogen-dependent tumour growth is the sole contribution of oestrogens to tumour development in the mammary gland, because oestrogen rece...

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Veröffentlicht in:	European journal of cancer prevention 1997-02, Vol.6 (1), p.3-10
1. Verfasser:	Liehr, J G
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Biotransformation Breast Neoplasms - etiology Breast Neoplasms - prevention & control Carcinogens - metabolism DNA Damage Estrogens, Conjugated (USP) - adverse effects Estrogens, Conjugated (USP) - metabolism Female Free Radicals - adverse effects Free Radicals - metabolism Gynecology. Andrology. Obstetrics Humans Mammary gland diseases Mammary Neoplasms, Animal - etiology Mammary Neoplasms, Animal - physiopathology Medical sciences REVIEW Risk Assessment Tumors
Online-Zugang:	Volltext
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