Plasma concentrations of risperidone and 9-hydroxyrisperidone during combined treatment with paroxetine

The effects of paroxetine on steady-state plasma concentrations of risperidone and its active metabolite 9-hydroxyrisperidone (9-OH-risperidone) were studied in 10 patients with schizophrenia or schizoaffective disorder. Patients stabilized using risperidone therapy (4-8 mg/d) also received paroxeti...

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Veröffentlicht in:	Therapeutic drug monitoring 2001-06, Vol.23 (3), p.223-227
Hauptverfasser:	SPINA, Edoardo, AVENOSO, Angela, FACCIOLA, Gabriella, SCORDO, Maria Gabriella, ANCIONE, Maria, MADIA, Aldo
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antipsychotic Agents - blood Biological and medical sciences Cytochrome P-450 CYP2D6 - physiology Drug Interactions Female Humans Isoxazoles - blood Male Medical sciences Middle Aged Neuropharmacology Paliperidone Palmitate Paroxetine - administration & dosage Pharmacology. Drug treatments Psycholeptics: tranquillizer, neuroleptic Psychology. Psychoanalysis. Psychiatry Psychopharmacology Pyrimidines - blood Risperidone - administration & dosage Risperidone - blood Serotonin Uptake Inhibitors - administration & dosage
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