Linear accelerator radiosurgery for meningiomas in and around the cavernous sinus

A retrospective study to evaluate the efficacy and side effects of linear accelerator radiosurgery in the treatment of cavernous sinus meningiomas. Between 1993 and 2001, 42 patients with meningiomas involving the cavernous sinus underwent linear accelerator radiosurgery at our institution. A mean r...

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Veröffentlicht in:Neurosurgery 2002-12, Vol.51 (6), p.1373-1380
Hauptverfasser: Spiegelmann, Roberto, Nissim, Ouzi, Menhel, Janna, Alezra, Dror, Pfeffer, M Raphael
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container_end_page 1380
container_issue 6
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container_title Neurosurgery
container_volume 51
creator Spiegelmann, Roberto
Nissim, Ouzi
Menhel, Janna
Alezra, Dror
Pfeffer, M Raphael
description A retrospective study to evaluate the efficacy and side effects of linear accelerator radiosurgery in the treatment of cavernous sinus meningiomas. Between 1993 and 2001, 42 patients with meningiomas involving the cavernous sinus underwent linear accelerator radiosurgery at our institution. A mean radiation dose of 14 Gy was delivered to the tumor margin. The median tumor volume was 8.2 cm3 (mean, 8.4 cm3). Median follow-up was 36 months (mean, 38 mo). Control of tumor growth was achieved in 97.5% of the patients. There was no mortality or permanent extraocular motor or pituitary dysfunction. Treatment-related complications included new trigeminal neuropathy in 4.7% and a new visual field defect in 2.8%. Two patients required shunt placement after developing hydrocephalus. One patient with symptomatic temporal lobe edema underwent partial excision of the tumor. Improvement of existing cranial neuropathies was noted in 29% of affected trigeminal nerves, in 22% of oculomotor nerves, and in 13% of Cranial Nerves IV and VI. This study indicates that linear accelerator radiosurgery can achieve a high control rate of meningiomas involving the cavernous sinus with no mortality and a low incidence of morbidity.
doi_str_mv 10.1097/00006123-200212000-00007
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source Journals@Ovid Ovid Autoload; MEDLINE
subjects Adult
Aged
Aged, 80 and over
Cavernous Sinus - surgery
Cranial Nerve Diseases - surgery
Humans
Magnetic Resonance Imaging
Meningeal Neoplasms - diagnosis
Meningeal Neoplasms - surgery
Meningioma - diagnosis
Meningioma - surgery
Middle Aged
Particle Accelerators
Radiosurgery - adverse effects
Treatment Outcome
title Linear accelerator radiosurgery for meningiomas in and around the cavernous sinus
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