ETA Receptors Mediate Vasoconstriction of Large Conduit Arteries During Reduced Flow in Humans

Vascular tone is regulated by endothelium-derived vasodilating and constricting substances, mainly nitric oxide and endothelin (ET)-1. These 2 mediators, which antagonize the actions of each other, are released in response to shear-stress produced by blood flow. The aim of this study was to delineat...

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Veröffentlicht in:	Journal of cardiovascular pharmacology 2003-09, Vol.42 (3), p.315-318
Hauptverfasser:	Spieker, Lukas E, Lüscher, Thomas F, Noll, Georg
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Cardiovascular system Drug Interactions Endothelin Receptor Antagonists Endothelin-1 - physiology Humans Medical sciences Miscellaneous Nitric Oxide - physiology Peptides, Cyclic - pharmacology Pharmacology. Drug treatments Radial Artery - drug effects Radial Artery - physiology Regional Blood Flow - drug effects Vasoconstriction - physiology Vasodilation - drug effects
Online-Zugang:	Volltext
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