Effects of AH-1058, a New Antiarrhythmic Drug, on Experimental Arrhythmias and Cardiac Membrane Currents

AH-1058 is a newly synthesized antiarrhythmic agent. We investigated the antiarrhythmic and electrophysiological effects of AH-1058 in experimental arrhythmia models and isolated cardiomyocytes. In the ouabain-induced arrhythmia model of the guinea pig, pretreatment with AH-1058 (0.1-0.3 mg/kg, i.v....

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of cardiovascular pharmacology 1999-04, Vol.33 (4), p.625-632
Hauptverfasser:	Takahara, Akira, Uneyama, Hisayuki, Sasaki, Noriko, Ueda, Hiroko, Dohmoto, Hideki, Shoji, Masataka, Hara, Yukio, Nakaya, Haruaki, Yoshimoto, Ryota
Format:	Artikel
Sprache:	eng
Schlagworte:	Aconitine - pharmacology Animals Anti-Arrhythmia Agents - pharmacology Anti-Arrhythmia Agents - therapeutic use Antiarythmic agents Arrhythmias, Cardiac - chemically induced Arrhythmias, Cardiac - drug therapy Biological and medical sciences Bridged Bicyclo Compounds - pharmacology Bridged Bicyclo Compounds - therapeutic use Cardiovascular system Electrophysiology Female Guinea Pigs Male Medical sciences Membrane Potentials - drug effects Ouabain - pharmacology Perfusion Pharmacology. Drug treatments Piperidines - pharmacology Piperidines - therapeutic use Rats Rats, Sprague-Dawley
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!