Prevention of Rethrombosis After Coronary Thrombolysis in a Chronic Canine Model. II. Adjunctive Therapy with r-Hirudin

We examined the effectiveness of the direct-acting thrombin inhibitor, recombinant hirudin (r-hirudin), for prevention of coronary rethrombosis after thrombolysis with recombinant tissue plasminogen activator (rt-PA) in a canine model of coronary artery thrombosis. The reocclusion rate of 15–30% ass...

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Veröffentlicht in:Journal of cardiovascular pharmacology 1994-11, Vol.2 (2), p.203-211
Hauptverfasser: Rote, William E, Mu, Dun-Xue, Bates, Eric R, Nedelman, Mark A, Lucchesi, Benedict R
Format: Artikel
Sprache:eng
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