Comparison of Cardiovascular Actions of Dihydralazine, Phentolamine, and Prazosin in Spontaneously Hypertensive Rats

Intravenous administration of dihydralazine, phentolamine, or prazosin (0.3 mg/kg) produced similar decreases in blood pressure in pentobarbital-anesthetized spontaneously hypertensive rats (SHR), as well as in pithed SHR whose blood pressure had been raised by an i.v. infusion of cirazoline or by e...

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Veröffentlicht in:	Journal of cardiovascular pharmacology 1979-01, Vol.1 (1), p.19-30
Hauptverfasser:	Lefèvre-Borg, Françoise, Roach, Alan G, Cavero, Icilio
Format:	Artikel
Sprache:	eng
Schlagworte:	Anesthesia Animals Blood Pressure - drug effects Dihydralazine - pharmacology Drug Interactions Hemodynamics - drug effects Hydralazine - analogs & derivatives Hypertension - physiopathology Methysergide - pharmacology Phentolamine - pharmacology Prazosin - pharmacology Quinazolines - pharmacology Rats Receptors, Adrenergic, alpha - physiology Spinal Cord - physiology
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