Captopril treatment in elderly hypertensive patients: efficacy and tolerability

Ninety-five elderly (>70 years) hypertensive patients were treated for 3 months with 25-100 mg captopril daily. The mean blood pressure decrease was from 179/101 to 155/87 mmHg (P

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Veröffentlicht in:Journal of hypertension 1989-09, Vol.7 Suppl 7, p.S57-S58
Hauptverfasser: Giuntoli, Franco, Gabbani, Stefano, Natali, Alessandro, Galeone, Francesco, Saba, Paolo
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container_issue
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container_title Journal of hypertension
container_volume 7 Suppl 7
creator Giuntoli, Franco
Gabbani, Stefano
Natali, Alessandro
Galeone, Francesco
Saba, Paolo
description Ninety-five elderly (>70 years) hypertensive patients were treated for 3 months with 25-100 mg captopril daily. The mean blood pressure decrease was from 179/101 to 155/87 mmHg (P
doi_str_mv 10.1097/00004872-198909007-00013
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The mean blood pressure decrease was from 179/101 to 155/87 mmHg (P&lt;0.001). The heart rate did not change. The drug was generally well tolerated (patients taking &lt;100mg captopril or captopril + chlorthalidone reported side effects) and there was no change in the biochemical parameters (glucose, uric acid, cholesterol, high density lipoprotein-cholesterol, triglycerides, apoproteins, blood urea nitrogen, creatinine, serum electrolytes). Our open study indicates that captopril is a safe and effective antihypertensive agent in elderly patients. 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The mean blood pressure decrease was from 179/101 to 155/87 mmHg (P&lt;0.001). The heart rate did not change. The drug was generally well tolerated (patients taking &lt;100mg captopril or captopril + chlorthalidone reported side effects) and there was no change in the biochemical parameters (glucose, uric acid, cholesterol, high density lipoprotein-cholesterol, triglycerides, apoproteins, blood urea nitrogen, creatinine, serum electrolytes). Our open study indicates that captopril is a safe and effective antihypertensive agent in elderly patients. However, some caution is necessary when high doses of captopril (100mg/day) are used</description><subject>Antihypertensive agents</subject><subject>Biological and medical sciences</subject><subject>Cardiovascular system</subject><subject>Medical sciences</subject><subject>Pharmacology. 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source Journals@Ovid Complete
subjects Antihypertensive agents
Biological and medical sciences
Cardiovascular system
Medical sciences
Pharmacology. Drug treatments
title Captopril treatment in elderly hypertensive patients: efficacy and tolerability
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