Mirtazapine versus amitriptyline in the long-term treatment of depression: a double-blind placebo-controlled study

Of 580 patients randomly assigned to short-term, double-blind treatment with either mirtazapine, amitriptyline or placebo, a total of 217 patients clinically judged to be responders subsequently continued on the same medication for up to 2 years in the long-term treatment study (mirtazapine, n = 74;...

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