Laboratory Diagnostic Tests in Acute Pancreatitis
The diagnosis of acute pancreatitis depends on a combination of clinical assessment and laboratory testing. Although the serum amylase is the cornerstone laboratory test used in establishing the diagnosis of acute pancreatitis, there are limitations in the sensitivity and specificity that may be imp...
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| Veröffentlicht in: | Journal of clinical gastroenterology 2002-04, Vol.34 (4), p.459-462 |
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| container_end_page | 462 |
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| container_title | Journal of clinical gastroenterology |
| container_volume | 34 |
| creator | Smotkin, Joseph Tenner, Scott |
| description | The diagnosis of acute pancreatitis depends on a combination of clinical assessment and laboratory testing. Although the serum amylase is the cornerstone laboratory test used in establishing the diagnosis of acute pancreatitis, there are limitations in the sensitivity and specificity that may be important for the clinician to recognize. The serum lipase level may be especially useful in patients with alcohol-induced acute pancreatitis. A new urinary test strip that uses trypsinogen-2 may have a role in establishing the diagnosis of acute pancreatitis. In addition, several new laboratory tests and new interpretations of old laboratory tests may assist in establishing the etiology and severity of acute pancreatitis. This review summarizes important aspects of standard laboratory tests and novel laboratory approaches in establishing the diagnosis, etiology, and severity of acute pancreatitis. |
| doi_str_mv | 10.1097/00004836-200204000-00018 |
| format | Article |
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Although the serum amylase is the cornerstone laboratory test used in establishing the diagnosis of acute pancreatitis, there are limitations in the sensitivity and specificity that may be important for the clinician to recognize. The serum lipase level may be especially useful in patients with alcohol-induced acute pancreatitis. A new urinary test strip that uses trypsinogen-2 may have a role in establishing the diagnosis of acute pancreatitis. In addition, several new laboratory tests and new interpretations of old laboratory tests may assist in establishing the etiology and severity of acute pancreatitis. This review summarizes important aspects of standard laboratory tests and novel laboratory approaches in establishing the diagnosis, etiology, and severity of acute pancreatitis.</description><identifier>ISSN: 0192-0790</identifier><identifier>EISSN: 1539-2031</identifier><identifier>DOI: 10.1097/00004836-200204000-00018</identifier><identifier>PMID: 11907364</identifier><language>eng</language><publisher>United States: Lippincott Williams & Wilkins, Inc</publisher><subject>Acute Disease ; Alanine Transaminase - blood ; Amylases - blood ; Cholelithiasis - blood ; Cholelithiasis - complications ; Humans ; Lipase - blood ; Pancreatitis - blood ; Pancreatitis - diagnosis ; Pancreatitis - etiology ; Pancreatitis, Alcoholic - blood ; Pancreatitis, Alcoholic - diagnosis ; Sensitivity and Specificity ; Severity of Illness Index ; Trypsin ; Trypsinogen - blood ; Trypsinogen - urine</subject><ispartof>Journal of clinical gastroenterology, 2002-04, Vol.34 (4), p.459-462</ispartof><rights>2002 Lippincott Williams & Wilkins, Inc.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c2888-2bea1c6cc92d8bb47b8b03e807dd21f2d7834796e94a6029b0014d3637ab59933</citedby><cites>FETCH-LOGICAL-c2888-2bea1c6cc92d8bb47b8b03e807dd21f2d7834796e94a6029b0014d3637ab59933</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,778,782,27911,27912</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11907364$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Smotkin, Joseph</creatorcontrib><creatorcontrib>Tenner, Scott</creatorcontrib><title>Laboratory Diagnostic Tests in Acute Pancreatitis</title><title>Journal of clinical gastroenterology</title><addtitle>J Clin Gastroenterol</addtitle><description>The diagnosis of acute pancreatitis depends on a combination of clinical assessment and laboratory testing. Although the serum amylase is the cornerstone laboratory test used in establishing the diagnosis of acute pancreatitis, there are limitations in the sensitivity and specificity that may be important for the clinician to recognize. The serum lipase level may be especially useful in patients with alcohol-induced acute pancreatitis. A new urinary test strip that uses trypsinogen-2 may have a role in establishing the diagnosis of acute pancreatitis. In addition, several new laboratory tests and new interpretations of old laboratory tests may assist in establishing the etiology and severity of acute pancreatitis. This review summarizes important aspects of standard laboratory tests and novel laboratory approaches in establishing the diagnosis, etiology, and severity of acute pancreatitis.</description><subject>Acute Disease</subject><subject>Alanine Transaminase - blood</subject><subject>Amylases - blood</subject><subject>Cholelithiasis - blood</subject><subject>Cholelithiasis - complications</subject><subject>Humans</subject><subject>Lipase - blood</subject><subject>Pancreatitis - blood</subject><subject>Pancreatitis - diagnosis</subject><subject>Pancreatitis - etiology</subject><subject>Pancreatitis, Alcoholic - blood</subject><subject>Pancreatitis, Alcoholic - diagnosis</subject><subject>Sensitivity and Specificity</subject><subject>Severity of Illness Index</subject><subject>Trypsin</subject><subject>Trypsinogen - blood</subject><subject>Trypsinogen - urine</subject><issn>0192-0790</issn><issn>1539-2031</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2002</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kMFKAzEQhoMotlZfQfYFVieZdJMcS9UqFPRQzyHJpnZ12y1JltK3N9qqJweGYYb_H2Y-QgoKNxSUuIUcXGJVMgAGPHdlTipPyJCOUeUx0lMyBKpYCULBgFzE-J4VApGekwGlCgRWfEjo3NgumNSFfXHXmLdNF1PjioWPKRbNppi4PvnixWxc8CY1qYmX5Gxp2uivjnVEXh_uF9PHcv48e5pO5qVjUsqSWW-oq5xTrJbWcmGlBfQSRF0zumS1kMiFqrzipgKmbL6O11ihMHasFOKIyMNeF7oYg1_qbWjWJuw1Bf1FQf9Q0L8U9DeFbL0-WLe9Xfv6z3h8Owv4QbDr2uRD_Gj7nQ965U2bVvo_uvgJ-AZlwg</recordid><startdate>200204</startdate><enddate>200204</enddate><creator>Smotkin, Joseph</creator><creator>Tenner, Scott</creator><general>Lippincott Williams & Wilkins, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>200204</creationdate><title>Laboratory Diagnostic Tests in Acute Pancreatitis</title><author>Smotkin, Joseph ; Tenner, Scott</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c2888-2bea1c6cc92d8bb47b8b03e807dd21f2d7834796e94a6029b0014d3637ab59933</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2002</creationdate><topic>Acute Disease</topic><topic>Alanine Transaminase - blood</topic><topic>Amylases - blood</topic><topic>Cholelithiasis - blood</topic><topic>Cholelithiasis - complications</topic><topic>Humans</topic><topic>Lipase - blood</topic><topic>Pancreatitis - blood</topic><topic>Pancreatitis - diagnosis</topic><topic>Pancreatitis - etiology</topic><topic>Pancreatitis, Alcoholic - blood</topic><topic>Pancreatitis, Alcoholic - diagnosis</topic><topic>Sensitivity and Specificity</topic><topic>Severity of Illness Index</topic><topic>Trypsin</topic><topic>Trypsinogen - blood</topic><topic>Trypsinogen - urine</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Smotkin, Joseph</creatorcontrib><creatorcontrib>Tenner, Scott</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><jtitle>Journal of clinical gastroenterology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Smotkin, Joseph</au><au>Tenner, Scott</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Laboratory Diagnostic Tests in Acute Pancreatitis</atitle><jtitle>Journal of clinical gastroenterology</jtitle><addtitle>J Clin Gastroenterol</addtitle><date>2002-04</date><risdate>2002</risdate><volume>34</volume><issue>4</issue><spage>459</spage><epage>462</epage><pages>459-462</pages><issn>0192-0790</issn><eissn>1539-2031</eissn><abstract>The diagnosis of acute pancreatitis depends on a combination of clinical assessment and laboratory testing. 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| fulltext | fulltext |
| identifier | ISSN: 0192-0790 |
| ispartof | Journal of clinical gastroenterology, 2002-04, Vol.34 (4), p.459-462 |
| issn | 0192-0790 1539-2031 |
| language | eng |
| recordid | cdi_crossref_primary_10_1097_00004836_200204000_00018 |
| source | MEDLINE; Journals@Ovid Complete |
| subjects | Acute Disease Alanine Transaminase - blood Amylases - blood Cholelithiasis - blood Cholelithiasis - complications Humans Lipase - blood Pancreatitis - blood Pancreatitis - diagnosis Pancreatitis - etiology Pancreatitis, Alcoholic - blood Pancreatitis, Alcoholic - diagnosis Sensitivity and Specificity Severity of Illness Index Trypsin Trypsinogen - blood Trypsinogen - urine |
| title | Laboratory Diagnostic Tests in Acute Pancreatitis |
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