Clonazepam : sleep laboratory study of efficacy and withdrawal

Clonazepam 0.5 mg was evaluated in a sleep laboratory study of 6 insomniac patients. The 16-night protocol consisted of 4 placebo-baseline nights, 7 nights of drug administration and 5 placebo-withdrawal nights. Clonazepam produced a significant decrease in total wake time initially (nights 5-7), as...

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Veröffentlicht in:	Journal of clinical psychopharmacology 1991-06, Vol.11 (3), p.189-193
Hauptverfasser:	KALES, A, MANFREDI, R. L, VGONTZAS, A. N, BALDASSANO, C. F, KOSTAKOS, K, KALES, J. D
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Clonazepam - administration & dosage Clonazepam - adverse effects Clonazepam - therapeutic use Double-Blind Method Female Humans Hypnotics. Sedatives Male Medical sciences Middle Aged Neuropharmacology Pharmacology. Drug treatments Psychology. Psychoanalysis. Psychiatry Psychopharmacology Sleep - drug effects Sleep Initiation and Maintenance Disorders - drug therapy Substance Withdrawal Syndrome - etiology
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