Anticholinergic effects on memory: benztropine versus amantadine

To evaluate anticholinergic effects on cognition and other functions, we studied 60 healthy volunteers in a double-blind crossover trial of two antiparkinsonian agents, benztropine and amantadine. Benztropine 4 mg/day, but not amantadine 200 mg/day, impaired free recall and perception of time, and s...

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Veröffentlicht in:	Journal of clinical psychopharmacology 1989-06, Vol.9 (3), p.180-185
Hauptverfasser:	GELENBERG, A. J, VAN PUTTEN, T, LAVORI, P. W, WOJCIK, J. D, FALK, W. E, MARDER, S, GALVIN-NADEAU, M, SPRING, B, MOHS, R. C, BROTAMN, A. W
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Affect - drug effects Amantadine - toxicity Arousal - drug effects Attention - drug effects Benztropine - toxicity Biological and medical sciences Brain - drug effects Clinical Trials as Topic Double-Blind Method Drug toxicity and drugs side effects treatment Humans Male Medical sciences Memory - drug effects Mental Recall - drug effects Middle Aged Pharmacology. Drug treatments Random Allocation Receptors, Cholinergic - drug effects Retention (Psychology) - drug effects Salivation - drug effects Serial Learning - drug effects Toxicity: nervous system and muscle Tropanes - toxicity
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