Methylphenidate-induced hallucinosis: case histories and possible mechanisms of action
Published reports of toxic hallucinosis during treatment with methylphenidate are rare. Two cases are described and it is suggested that methylphenidate-induced hallucinosis is more common than has been appreciated. Symptoms may be understood in terms of dose-related effects at pre- and postsynaptic...
Gespeichert in:
| Veröffentlicht in: | Journal of developmental and behavioral pediatrics 1981-06, Vol.2 (2), p.35-38 |
|---|---|
| 1. Verfasser: | |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 38 |
|---|---|
| container_issue | 2 |
| container_start_page | 35 |
| container_title | Journal of developmental and behavioral pediatrics |
| container_volume | 2 |
| creator | Young, J G |
| description | Published reports of toxic hallucinosis during treatment with methylphenidate are rare. Two cases are described and it is suggested that methylphenidate-induced hallucinosis is more common than has been appreciated. Symptoms may be understood in terms of dose-related effects at pre- and postsynaptic receptors. Two other hypotheses that may clarify underlying mechanisms of action that produce toxic effects relate to (1) noradrenergic facilitation transmission of information in the visual pathway, and (2) interactions among brain monoamine systems. |
| doi_str_mv | 10.1097/00004703-198106000-00003 |
| format | Article |
| fullrecord | <record><control><sourceid>pubmed_cross</sourceid><recordid>TN_cdi_crossref_primary_10_1097_00004703_198106000_00003</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>7263866</sourcerecordid><originalsourceid>FETCH-LOGICAL-c170t-1140e205b6105302b4a78f9721feb6642d8dcb0a8bd06fcbfeb3b6fc6a9296603</originalsourceid><addsrcrecordid>eNo9kMtOwzAQRb0AlVL4BCT_gGFsp07MDlW8pCI2gNhFfkwUo7wUJ4v-PS4tnc3MHOmORocQyuGWg87vIFWWg2RcFxxU2tgeyTOyBK4VE6C-L8hljD-JCq7lgixyoWSh1JJ8veFU75qhxi54MyELnZ8delqbppld6PoY4j11JiKtQ5z6MWCkpvN06GMMtkHaoqtNF2IbaV9R46bQd1fkvDJNxOtjX5HPp8ePzQvbvj-_bh62zPEcJsZ5BihgbRWHtQRhM5MXlc4Fr9AqlQlfeGfBFNaDqpxNVNo0KKOFVgrkihSHu25M74xYlcMYWjPuSg7l3k75b6c82flDMkVvDtFhti36U_CoRv4C4rZjiQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>Methylphenidate-induced hallucinosis: case histories and possible mechanisms of action</title><source>MEDLINE</source><source>Journals@Ovid Complete</source><creator>Young, J G</creator><creatorcontrib>Young, J G</creatorcontrib><description>Published reports of toxic hallucinosis during treatment with methylphenidate are rare. Two cases are described and it is suggested that methylphenidate-induced hallucinosis is more common than has been appreciated. Symptoms may be understood in terms of dose-related effects at pre- and postsynaptic receptors. Two other hypotheses that may clarify underlying mechanisms of action that produce toxic effects relate to (1) noradrenergic facilitation transmission of information in the visual pathway, and (2) interactions among brain monoamine systems.</description><identifier>ISSN: 0196-206X</identifier><identifier>DOI: 10.1097/00004703-198106000-00003</identifier><identifier>PMID: 7263866</identifier><language>eng</language><publisher>United States</publisher><subject>Brain Chemistry - drug effects ; Child ; Dose-Response Relationship, Drug ; Hallucinations - chemically induced ; Humans ; Male ; Methylphenidate - adverse effects ; Norepinephrine - physiology ; Receptors, Dopamine - drug effects ; Vision, Ocular - drug effects</subject><ispartof>Journal of developmental and behavioral pediatrics, 1981-06, Vol.2 (2), p.35-38</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/7263866$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Young, J G</creatorcontrib><title>Methylphenidate-induced hallucinosis: case histories and possible mechanisms of action</title><title>Journal of developmental and behavioral pediatrics</title><addtitle>J Dev Behav Pediatr</addtitle><description>Published reports of toxic hallucinosis during treatment with methylphenidate are rare. Two cases are described and it is suggested that methylphenidate-induced hallucinosis is more common than has been appreciated. Symptoms may be understood in terms of dose-related effects at pre- and postsynaptic receptors. Two other hypotheses that may clarify underlying mechanisms of action that produce toxic effects relate to (1) noradrenergic facilitation transmission of information in the visual pathway, and (2) interactions among brain monoamine systems.</description><subject>Brain Chemistry - drug effects</subject><subject>Child</subject><subject>Dose-Response Relationship, Drug</subject><subject>Hallucinations - chemically induced</subject><subject>Humans</subject><subject>Male</subject><subject>Methylphenidate - adverse effects</subject><subject>Norepinephrine - physiology</subject><subject>Receptors, Dopamine - drug effects</subject><subject>Vision, Ocular - drug effects</subject><issn>0196-206X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1981</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kMtOwzAQRb0AlVL4BCT_gGFsp07MDlW8pCI2gNhFfkwUo7wUJ4v-PS4tnc3MHOmORocQyuGWg87vIFWWg2RcFxxU2tgeyTOyBK4VE6C-L8hljD-JCq7lgixyoWSh1JJ8veFU75qhxi54MyELnZ8delqbppld6PoY4j11JiKtQ5z6MWCkpvN06GMMtkHaoqtNF2IbaV9R46bQd1fkvDJNxOtjX5HPp8ePzQvbvj-_bh62zPEcJsZ5BihgbRWHtQRhM5MXlc4Fr9AqlQlfeGfBFNaDqpxNVNo0KKOFVgrkihSHu25M74xYlcMYWjPuSg7l3k75b6c82flDMkVvDtFhti36U_CoRv4C4rZjiQ</recordid><startdate>198106</startdate><enddate>198106</enddate><creator>Young, J G</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>198106</creationdate><title>Methylphenidate-induced hallucinosis: case histories and possible mechanisms of action</title><author>Young, J G</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c170t-1140e205b6105302b4a78f9721feb6642d8dcb0a8bd06fcbfeb3b6fc6a9296603</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1981</creationdate><topic>Brain Chemistry - drug effects</topic><topic>Child</topic><topic>Dose-Response Relationship, Drug</topic><topic>Hallucinations - chemically induced</topic><topic>Humans</topic><topic>Male</topic><topic>Methylphenidate - adverse effects</topic><topic>Norepinephrine - physiology</topic><topic>Receptors, Dopamine - drug effects</topic><topic>Vision, Ocular - drug effects</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Young, J G</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><jtitle>Journal of developmental and behavioral pediatrics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Young, J G</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Methylphenidate-induced hallucinosis: case histories and possible mechanisms of action</atitle><jtitle>Journal of developmental and behavioral pediatrics</jtitle><addtitle>J Dev Behav Pediatr</addtitle><date>1981-06</date><risdate>1981</risdate><volume>2</volume><issue>2</issue><spage>35</spage><epage>38</epage><pages>35-38</pages><issn>0196-206X</issn><abstract>Published reports of toxic hallucinosis during treatment with methylphenidate are rare. Two cases are described and it is suggested that methylphenidate-induced hallucinosis is more common than has been appreciated. Symptoms may be understood in terms of dose-related effects at pre- and postsynaptic receptors. Two other hypotheses that may clarify underlying mechanisms of action that produce toxic effects relate to (1) noradrenergic facilitation transmission of information in the visual pathway, and (2) interactions among brain monoamine systems.</abstract><cop>United States</cop><pmid>7263866</pmid><doi>10.1097/00004703-198106000-00003</doi><tpages>4</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0196-206X |
| ispartof | Journal of developmental and behavioral pediatrics, 1981-06, Vol.2 (2), p.35-38 |
| issn | 0196-206X |
| language | eng |
| recordid | cdi_crossref_primary_10_1097_00004703_198106000_00003 |
| source | MEDLINE; Journals@Ovid Complete |
| subjects | Brain Chemistry - drug effects Child Dose-Response Relationship, Drug Hallucinations - chemically induced Humans Male Methylphenidate - adverse effects Norepinephrine - physiology Receptors, Dopamine - drug effects Vision, Ocular - drug effects |
| title | Methylphenidate-induced hallucinosis: case histories and possible mechanisms of action |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-24T03%3A39%3A34IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-pubmed_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Methylphenidate-induced%20hallucinosis:%20case%20histories%20and%20possible%20mechanisms%20of%20action&rft.jtitle=Journal%20of%20developmental%20and%20behavioral%20pediatrics&rft.au=Young,%20J%20G&rft.date=1981-06&rft.volume=2&rft.issue=2&rft.spage=35&rft.epage=38&rft.pages=35-38&rft.issn=0196-206X&rft_id=info:doi/10.1097/00004703-198106000-00003&rft_dat=%3Cpubmed_cross%3E7263866%3C/pubmed_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/7263866&rfr_iscdi=true |