Estrogen Reduces Leukocyte Adhesion in the Cerebral Circulation of Female Rats

In this study the authors addressed the hypothesis that estrogen (i.e., 17β-estradiol) acts to repress leukocyte adhesion, The experiments involved comparing leukocyte adhesion in cerebral venules in vivo, in intact ovariectomized and 17β-estradiol-treated (100 μ/kg/day for 1 week) ovariectomized fe...

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Veröffentlicht in:	Journal of cerebral blood flow and metabolism 1999-10, Vol.19 (10), p.1061-1065
Hauptverfasser:	Santizo, Roberto, Pelligrino, Dale A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Blood Gas Analysis Carcinogens - pharmacology Cell Adhesion - drug effects Cell Adhesion - immunology Cerebrovascular Circulation - immunology Estradiol - pharmacology Female Fundamental and applied biological sciences. Psychology Hormone metabolism and regulation Leukocytes - cytology Leukocytes - drug effects Leukocytes - enzymology Mammalian female genital system Nitric Oxide Synthase - metabolism Nitric Oxide Synthase Type III Ovariectomy Pia Mater - blood supply Rats Rats, Sprague-Dawley Tetradecanoylphorbol Acetate - pharmacology Vertebrates: reproduction
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