The Importance of Sodium Concentration on the Incidence of Fibrillation During Coronary Arteriography in Dogs
Coronary arteriography is known to produce electrical disturbances including conduction disturbances, arrhythmias, and ventricular fibrillation. A canine model for studying ventricular fibrillation has been developed that uses relatively long injections in the right coronary artery. In experiments i...
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| Veröffentlicht in: | Investigative radiology 1988-09, Vol.23 Suppl 1, p.S137-S139 |
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| container_title | Investigative radiology |
| container_volume | 23 Suppl 1 |
| creator | MORRIS, THOMAS W |
| description | Coronary arteriography is known to produce electrical disturbances including conduction disturbances, arrhythmias, and ventricular fibrillation. A canine model for studying ventricular fibrillation has been developed that uses relatively long injections in the right coronary artery. In experiments in 49 dogs over a five-year period, the authors have consistently observed that with low osmolality contrast media, the incidence of ventricular fibrillation becomes quite high when the formulation contains less than 3.2 mmol/L sodium. This effect seems independent of the concentration of the contrast media molecules. High concentrations of the ionic monomer diatrizoate cause fibrillation despite high sodium concentrations. |
| doi_str_mv | 10.1097/00004424-198809001-00019 |
| format | Article |
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A canine model for studying ventricular fibrillation has been developed that uses relatively long injections in the right coronary artery. In experiments in 49 dogs over a five-year period, the authors have consistently observed that with low osmolality contrast media, the incidence of ventricular fibrillation becomes quite high when the formulation contains less than 3.2 mmol/L sodium. This effect seems independent of the concentration of the contrast media molecules. High concentrations of the ionic monomer diatrizoate cause fibrillation despite high sodium concentrations.</description><identifier>ISSN: 0020-9996</identifier><identifier>EISSN: 1536-0210</identifier><identifier>DOI: 10.1097/00004424-198809001-00019</identifier><identifier>PMID: 3198333</identifier><language>eng</language><publisher>United States: Lippincott-Raven Publishers</publisher><subject>Angiography ; Animals ; Contrast Media - toxicity ; Coronary Angiography ; Dogs ; Female ; Injections, Intra-Arterial ; Male ; Osmolar Concentration ; Sodium - pharmacology ; Time Factors ; Ventricular Fibrillation - chemically induced</subject><ispartof>Investigative radiology, 1988-09, Vol.23 Suppl 1, p.S137-S139</ispartof><rights>Lippincott-Raven Publishers.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3369-907fb6f1360f6d02c1322fd082f7cfe6a29e97d0dd8f72b3f8c0cc6933ac304c3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,777,781,27905,27906</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/3198333$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>MORRIS, THOMAS W</creatorcontrib><title>The Importance of Sodium Concentration on the Incidence of Fibrillation During Coronary Arteriography in Dogs</title><title>Investigative radiology</title><addtitle>Invest Radiol</addtitle><description>Coronary arteriography is known to produce electrical disturbances including conduction disturbances, arrhythmias, and ventricular fibrillation. A canine model for studying ventricular fibrillation has been developed that uses relatively long injections in the right coronary artery. In experiments in 49 dogs over a five-year period, the authors have consistently observed that with low osmolality contrast media, the incidence of ventricular fibrillation becomes quite high when the formulation contains less than 3.2 mmol/L sodium. This effect seems independent of the concentration of the contrast media molecules. High concentrations of the ionic monomer diatrizoate cause fibrillation despite high sodium concentrations.</description><subject>Angiography</subject><subject>Animals</subject><subject>Contrast Media - toxicity</subject><subject>Coronary Angiography</subject><subject>Dogs</subject><subject>Female</subject><subject>Injections, Intra-Arterial</subject><subject>Male</subject><subject>Osmolar Concentration</subject><subject>Sodium - pharmacology</subject><subject>Time Factors</subject><subject>Ventricular Fibrillation - chemically induced</subject><issn>0020-9996</issn><issn>1536-0210</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1988</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kd9OwyAUh4nRzDl9BJO-QPUAlZbLZTpdssQL5zWh_NnQtjS0zbK3l9m5OwkJgfN9J_ADoQTDAwaeP0IcWUayFPOiAA6A03iC-QWa4ifKUiAYLtEUgEDKOWfX6KbrviJCcqATNKHRo5ROUb3ZmWRVtz70slEm8Tb58NoNdbLwcd_0QfbON0mc_ZFslNPmBC5dGVxVjcDzEFyzjVbwjQyHZB56E5zfBtnuDomLgN92t-jKyqozd6d1hj6XL5vFW7p-f10t5utUUcp4yiG3JbOYMrBMA1GYEmI1FMTmyhomCTc816B1YXNSUlsoUIpxSqWikCk6Q8XYVwXfdcFY0QZXx2sJDOIYoPgLUJwDFL8BRvV-VNuhrI0-i6fEYj0b63tfxRd239WwN0HsjKz6nfjvX-gPsUR8aw</recordid><startdate>198809</startdate><enddate>198809</enddate><creator>MORRIS, THOMAS W</creator><general>Lippincott-Raven Publishers</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>198809</creationdate><title>The Importance of Sodium Concentration on the Incidence of Fibrillation During Coronary Arteriography in Dogs</title><author>MORRIS, THOMAS W</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3369-907fb6f1360f6d02c1322fd082f7cfe6a29e97d0dd8f72b3f8c0cc6933ac304c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1988</creationdate><topic>Angiography</topic><topic>Animals</topic><topic>Contrast Media - toxicity</topic><topic>Coronary Angiography</topic><topic>Dogs</topic><topic>Female</topic><topic>Injections, Intra-Arterial</topic><topic>Male</topic><topic>Osmolar Concentration</topic><topic>Sodium - pharmacology</topic><topic>Time Factors</topic><topic>Ventricular Fibrillation - chemically induced</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>MORRIS, THOMAS W</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><jtitle>Investigative radiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>MORRIS, THOMAS W</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The Importance of Sodium Concentration on the Incidence of Fibrillation During Coronary Arteriography in Dogs</atitle><jtitle>Investigative radiology</jtitle><addtitle>Invest Radiol</addtitle><date>1988-09</date><risdate>1988</risdate><volume>23 Suppl 1</volume><spage>S137</spage><epage>S139</epage><pages>S137-S139</pages><issn>0020-9996</issn><eissn>1536-0210</eissn><abstract>Coronary arteriography is known to produce electrical disturbances including conduction disturbances, arrhythmias, and ventricular fibrillation. A canine model for studying ventricular fibrillation has been developed that uses relatively long injections in the right coronary artery. In experiments in 49 dogs over a five-year period, the authors have consistently observed that with low osmolality contrast media, the incidence of ventricular fibrillation becomes quite high when the formulation contains less than 3.2 mmol/L sodium. This effect seems independent of the concentration of the contrast media molecules. High concentrations of the ionic monomer diatrizoate cause fibrillation despite high sodium concentrations.</abstract><cop>United States</cop><pub>Lippincott-Raven Publishers</pub><pmid>3198333</pmid><doi>10.1097/00004424-198809001-00019</doi></addata></record> |
| fulltext | fulltext |
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| ispartof | Investigative radiology, 1988-09, Vol.23 Suppl 1, p.S137-S139 |
| issn | 0020-9996 1536-0210 |
| language | eng |
| recordid | cdi_crossref_primary_10_1097_00004424_198809001_00019 |
| source | MEDLINE; Journals@Ovid Complete |
| subjects | Angiography Animals Contrast Media - toxicity Coronary Angiography Dogs Female Injections, Intra-Arterial Male Osmolar Concentration Sodium - pharmacology Time Factors Ventricular Fibrillation - chemically induced |
| title | The Importance of Sodium Concentration on the Incidence of Fibrillation During Coronary Arteriography in Dogs |
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