Diatrizoate Contrast Agents: Studies on the Metabolism of Diacetamido-, 3-Amino-5-acetamido-, and 3,5-Diamino-2,4,6-triiodobenzoates

We have examined the metabolic behavior of several triiodobenzoic acid derivatives because of the observed mutagenicity and cytotoxicity of 3-amino-5-acetamido-2,4,6-triiodobenzoate (I) and 3,5-diamino-2,4,6-triiodobenzoate (II). Measurements were facilitated using iodine-131 (I)-labeled compounds....

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Veröffentlicht in:Investigative radiology 1981-11, Vol.16 (6), p.517-524
Hauptverfasser: WEISS, ROBERT, HSU, BENJAMIN, WHEELER, LARRY, NORMAN, AMOS, RILEY, RICHARD F
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Sprache:eng
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