Neuroaudiological Effects in a Case of Fatal Dimethylmercury Poisoning
OBJECTIVE:The audiological examination of this patient was to determine the degree and type of hearing loss that was incurred from apparent dimethylmercury poisoning. DESIGN:This was a single subject case study design. Audiologic tests were selected to help determine sensory from neural and/or centr...
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| Veröffentlicht in: | Ear and hearing 1999-06, Vol.20 (3), p.271-271 |
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| container_title | Ear and hearing |
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| creator | Musiek, Frank E Hanlon, David P |
| description | OBJECTIVE:The audiological examination of this patient was to determine the degree and type of hearing loss that was incurred from apparent dimethylmercury poisoning.
DESIGN:This was a single subject case study design. Audiologic tests were selected to help determine sensory from neural and/or central auditory system dysfunction.
RESULTS:This patient demonstrated an inability to understand speech, both in formal and informal assessments, yet relatively good hearing sensitivity for pure tones bilaterally. Distortion product otoacoustic emissions showed only minimal deficits in each ear. The auditory brain stem response was abnormal bilaterally, indicating neural and/or central involvement.
CONCLUSION:Dimethylmercury poisoning, in this case, resulted in compromise of the auditory neural system with little effect on the sensory (cochlea) mechanism. |
| doi_str_mv | 10.1097/00003446-199906000-00009 |
| format | Article |
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DESIGN:This was a single subject case study design. Audiologic tests were selected to help determine sensory from neural and/or central auditory system dysfunction.
RESULTS:This patient demonstrated an inability to understand speech, both in formal and informal assessments, yet relatively good hearing sensitivity for pure tones bilaterally. Distortion product otoacoustic emissions showed only minimal deficits in each ear. The auditory brain stem response was abnormal bilaterally, indicating neural and/or central involvement.
CONCLUSION:Dimethylmercury poisoning, in this case, resulted in compromise of the auditory neural system with little effect on the sensory (cochlea) mechanism.</description><identifier>ISSN: 0196-0202</identifier><identifier>EISSN: 1538-4667</identifier><identifier>DOI: 10.1097/00003446-199906000-00009</identifier><identifier>PMID: 10386853</identifier><identifier>CODEN: EAHEDS</identifier><language>eng</language><publisher>Baltimore, MD: Lippincott Williams & Wilkins, Inc</publisher><subject>Audiometry, Evoked Response ; Audiometry, Pure-Tone ; Biological and medical sciences ; Chemical and industrial products toxicology. Toxic occupational diseases ; Cochlea - drug effects ; Ear, auditive nerve, cochleovestibular tract, facial nerve: diseases, semeiology ; Evoked Potentials, Auditory, Brain Stem - drug effects ; Hearing Loss, Sensorineural - chemically induced ; Hearing Loss, Sensorineural - diagnosis ; Humans ; Male ; Medical sciences ; Methylmercury Compounds - poisoning ; Middle Aged ; Mutagens - poisoning ; Non tumoral diseases ; Otoacoustic Emissions, Spontaneous - drug effects ; Otorhinolaryngology. Stomatology ; Severity of Illness Index ; Toxicology ; Various organic compounds ; Vestibulocochlear Nerve - drug effects</subject><ispartof>Ear and hearing, 1999-06, Vol.20 (3), p.271-271</ispartof><rights>1999 Lippincott Williams & Wilkins, Inc.</rights><rights>1999 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3859-38c811c0ced5474364a232c8786a868ddd05487c7fc37d96e3b54a6010353de33</citedby><cites>FETCH-LOGICAL-c3859-38c811c0ced5474364a232c8786a868ddd05487c7fc37d96e3b54a6010353de33</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=1846222$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/10386853$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Musiek, Frank E</creatorcontrib><creatorcontrib>Hanlon, David P</creatorcontrib><title>Neuroaudiological Effects in a Case of Fatal Dimethylmercury Poisoning</title><title>Ear and hearing</title><addtitle>Ear Hear</addtitle><description>OBJECTIVE:The audiological examination of this patient was to determine the degree and type of hearing loss that was incurred from apparent dimethylmercury poisoning.
DESIGN:This was a single subject case study design. Audiologic tests were selected to help determine sensory from neural and/or central auditory system dysfunction.
RESULTS:This patient demonstrated an inability to understand speech, both in formal and informal assessments, yet relatively good hearing sensitivity for pure tones bilaterally. Distortion product otoacoustic emissions showed only minimal deficits in each ear. The auditory brain stem response was abnormal bilaterally, indicating neural and/or central involvement.
CONCLUSION:Dimethylmercury poisoning, in this case, resulted in compromise of the auditory neural system with little effect on the sensory (cochlea) mechanism.</description><subject>Audiometry, Evoked Response</subject><subject>Audiometry, Pure-Tone</subject><subject>Biological and medical sciences</subject><subject>Chemical and industrial products toxicology. Toxic occupational diseases</subject><subject>Cochlea - drug effects</subject><subject>Ear, auditive nerve, cochleovestibular tract, facial nerve: diseases, semeiology</subject><subject>Evoked Potentials, Auditory, Brain Stem - drug effects</subject><subject>Hearing Loss, Sensorineural - chemically induced</subject><subject>Hearing Loss, Sensorineural - diagnosis</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Methylmercury Compounds - poisoning</subject><subject>Middle Aged</subject><subject>Mutagens - poisoning</subject><subject>Non tumoral diseases</subject><subject>Otoacoustic Emissions, Spontaneous - drug effects</subject><subject>Otorhinolaryngology. Stomatology</subject><subject>Severity of Illness Index</subject><subject>Toxicology</subject><subject>Various organic compounds</subject><subject>Vestibulocochlear Nerve - drug effects</subject><issn>0196-0202</issn><issn>1538-4667</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1999</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kctOAyEUhonR2Fp9BcPC7Si3YWBpaqsmjbrQ9YQC06IzQwMzafr2UqdeNrIhnPP9JycfAECMrjGSxQ1KhzLGMyylRDy9sn1JHoExzqnIGOfFMRgjLHmGCCIjcBbjO0KYSM5OwQgjKrjI6RjMn2wfvOqN87VfOa1qOKsqq7sIXQsVnKpooa_gXHWpdeca2613dWOD7sMOvngXfeva1Tk4qVQd7cXhnoC3-ex1-pAtnu8fp7eLTFORy4wKLTDWSFuTs4JRzhShRItCcJUWMsagnIlCF5WmhZHc0mXOFEdp35waS-kEiGGuDj7GYKtyE1yjwq7EqNyrKb_VlD9qvkoyRS-H6KZfNtb8CQ4uEnB1AFRMHqqgWu3iLycYJ4QkjA3Y1tedDfGj7rc2lGur6m5d_vcz9BNgs3nw</recordid><startdate>199906</startdate><enddate>199906</enddate><creator>Musiek, Frank E</creator><creator>Hanlon, David P</creator><general>Lippincott Williams & Wilkins, Inc</general><general>Lippincott Williams & Wilkins</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>199906</creationdate><title>Neuroaudiological Effects in a Case of Fatal Dimethylmercury Poisoning</title><author>Musiek, Frank E ; Hanlon, David P</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3859-38c811c0ced5474364a232c8786a868ddd05487c7fc37d96e3b54a6010353de33</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1999</creationdate><topic>Audiometry, Evoked Response</topic><topic>Audiometry, Pure-Tone</topic><topic>Biological and medical sciences</topic><topic>Chemical and industrial products toxicology. Toxic occupational diseases</topic><topic>Cochlea - drug effects</topic><topic>Ear, auditive nerve, cochleovestibular tract, facial nerve: diseases, semeiology</topic><topic>Evoked Potentials, Auditory, Brain Stem - drug effects</topic><topic>Hearing Loss, Sensorineural - chemically induced</topic><topic>Hearing Loss, Sensorineural - diagnosis</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Methylmercury Compounds - poisoning</topic><topic>Middle Aged</topic><topic>Mutagens - poisoning</topic><topic>Non tumoral diseases</topic><topic>Otoacoustic Emissions, Spontaneous - drug effects</topic><topic>Otorhinolaryngology. Stomatology</topic><topic>Severity of Illness Index</topic><topic>Toxicology</topic><topic>Various organic compounds</topic><topic>Vestibulocochlear Nerve - drug effects</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Musiek, Frank E</creatorcontrib><creatorcontrib>Hanlon, David P</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><jtitle>Ear and hearing</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Musiek, Frank E</au><au>Hanlon, David P</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Neuroaudiological Effects in a Case of Fatal Dimethylmercury Poisoning</atitle><jtitle>Ear and hearing</jtitle><addtitle>Ear Hear</addtitle><date>1999-06</date><risdate>1999</risdate><volume>20</volume><issue>3</issue><spage>271</spage><epage>271</epage><pages>271-271</pages><issn>0196-0202</issn><eissn>1538-4667</eissn><coden>EAHEDS</coden><abstract>OBJECTIVE:The audiological examination of this patient was to determine the degree and type of hearing loss that was incurred from apparent dimethylmercury poisoning.
DESIGN:This was a single subject case study design. Audiologic tests were selected to help determine sensory from neural and/or central auditory system dysfunction.
RESULTS:This patient demonstrated an inability to understand speech, both in formal and informal assessments, yet relatively good hearing sensitivity for pure tones bilaterally. Distortion product otoacoustic emissions showed only minimal deficits in each ear. The auditory brain stem response was abnormal bilaterally, indicating neural and/or central involvement.
CONCLUSION:Dimethylmercury poisoning, in this case, resulted in compromise of the auditory neural system with little effect on the sensory (cochlea) mechanism.</abstract><cop>Baltimore, MD</cop><pub>Lippincott Williams & Wilkins, Inc</pub><pmid>10386853</pmid><doi>10.1097/00003446-199906000-00009</doi><tpages>1</tpages></addata></record> |
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| identifier | ISSN: 0196-0202 |
| ispartof | Ear and hearing, 1999-06, Vol.20 (3), p.271-271 |
| issn | 0196-0202 1538-4667 |
| language | eng |
| recordid | cdi_crossref_primary_10_1097_00003446_199906000_00009 |
| source | MEDLINE; Journals@Ovid Complete |
| subjects | Audiometry, Evoked Response Audiometry, Pure-Tone Biological and medical sciences Chemical and industrial products toxicology. Toxic occupational diseases Cochlea - drug effects Ear, auditive nerve, cochleovestibular tract, facial nerve: diseases, semeiology Evoked Potentials, Auditory, Brain Stem - drug effects Hearing Loss, Sensorineural - chemically induced Hearing Loss, Sensorineural - diagnosis Humans Male Medical sciences Methylmercury Compounds - poisoning Middle Aged Mutagens - poisoning Non tumoral diseases Otoacoustic Emissions, Spontaneous - drug effects Otorhinolaryngology. Stomatology Severity of Illness Index Toxicology Various organic compounds Vestibulocochlear Nerve - drug effects |
| title | Neuroaudiological Effects in a Case of Fatal Dimethylmercury Poisoning |
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