Confirmatory interleukin-1 receptor antagonist trial in severe sepsis: A phase III, randomized, doubleblind, placebo-controlled, multicenter trial

OBJECTIVE To determine the therapeutic efficacy and safety of recombinant human interleukin-1 receptor antagonist (rhIL-1ra) in the treatment of patients with severe sepsis. DESIGN Prospective, randomized, double-blind, placebo-controlled, multicenter trial with a planned, midstudy, interim analysis...

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Veröffentlicht in:	Critical care medicine 1997-07, Vol.25 (7), p.1115-1124
Hauptverfasser:	Opal, Steven M, Fisher, Charles J, Dhainaut, Jean-Francois A, Vincent, Jean-Louis, Brase, Rainer, Lowry, Stephen F, Sadoff, Jerald C, Slotman, Gus J, Levy, Howard, Balk, Robert A, Shelly, Maire P, Pribble, John P, LaBrecque, John F, Lookabaugh, Janice, Donovan, Hugh, Dubin, Howard, Baughman, Robert, Norman, James, DeMaria, Eric, Matzel, Klaus, Abraham, Edward, Seneff, Michael
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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