Suppression of Human Corneal Epithelial Proliferation with Breast Carcinoma Immunotoxin

We examined the effects of the immunotoxin 260F9 Mabrecombinant ricin A (developed against human breast carcinoma) on proliferating and confluent human corneal epithelium (HCE) cells in vitro. HCE cells derived from explants of discarded human donor corneoscleral rims were established as proliferati...

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Veröffentlicht in:	Cornea 1993-09, Vol.12 (5), p.391-396
Hauptverfasser:	Fulcher, Samuel, Foulks, Gary N, Wilkerson, Mark, Cobo, L Michael, Houston, L L, Hatchell, Diane
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Monoclonal - immunology Antigens, Neoplasm - immunology Breast Neoplasms - immunology Carcinoma - immunology Cell Count Cell Division - drug effects Cells, Cultured Cornea - cytology DNA - biosynthesis DNA Replication - drug effects Female Humans Immunotoxins - pharmacology Mice Mice, Inbred BALB C Recombinant Proteins - pharmacology Ricin - pharmacology
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