Fixation of experimental osteotomy of the distal femur with biodegradable thread in rabbits
A distal femoral osteotomy on 24 rabbits was fixed with biodegradable polyglycolic acid (PGA) thread pulled through drill holes made on both sides of the osteotomy. Follow-up times were one, three, six, 12 and 24 weeks. The distal part of each femur was removed, fixed in alcohol, embedded in methylm...
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| Veröffentlicht in: | Clinical orthopaedics and related research 1987-08, Vol.221 (221), p.297-303 |
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| container_title | Clinical orthopaedics and related research |
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| creator | VIHTONEN, K VAINIONPAA, S MERO, M PATIALA, H ROKKANEN, P KILPIKARI, J TORMALA, P |
| description | A distal femoral osteotomy on 24 rabbits was fixed with biodegradable polyglycolic acid (PGA) thread pulled through drill holes made on both sides of the osteotomy. Follow-up times were one, three, six, 12 and 24 weeks. The distal part of each femur was removed, fixed in alcohol, embedded in methylmethacrylate, sawed to 80 microns thick for oxytetracycline (OTC)-labeling studies and microradiography, and sectioned at 5 microns for histologic studies. As judged by histologic microradiographic, and OTC-labeling studies, 19 of 24 osteotomies were healing normally; after six weeks of follow-up examination, union of 11 of 14 osteotomies was observed on radiographs. On the basis of the present study, PGA threads may be promising for the fixation of osteotomies of the metaphyseal cancellous bone in rabbits. |
| doi_str_mv | 10.1097/00003086-198708000-00040 |
| format | Article |
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Follow-up times were one, three, six, 12 and 24 weeks. The distal part of each femur was removed, fixed in alcohol, embedded in methylmethacrylate, sawed to 80 microns thick for oxytetracycline (OTC)-labeling studies and microradiography, and sectioned at 5 microns for histologic studies. As judged by histologic microradiographic, and OTC-labeling studies, 19 of 24 osteotomies were healing normally; after six weeks of follow-up examination, union of 11 of 14 osteotomies was observed on radiographs. On the basis of the present study, PGA threads may be promising for the fixation of osteotomies of the metaphyseal cancellous bone in rabbits.</description><identifier>ISSN: 0009-921X</identifier><identifier>EISSN: 1528-1132</identifier><identifier>DOI: 10.1097/00003086-198708000-00040</identifier><identifier>PMID: 3038446</identifier><identifier>CODEN: CORTBR</identifier><language>eng</language><publisher>Heidelberg: Springer</publisher><subject>Animals ; Biodegradation, Environmental ; Biological and medical sciences ; Female ; Femur - anatomy & histology ; Femur - surgery ; Follow-Up Studies ; Male ; Medical sciences ; Orthopedic surgery ; Osteotomy - methods ; Polyglycolic Acid - metabolism ; Rabbits ; Surgery (general aspects). Transplantations, organ and tissue grafts. 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Follow-up times were one, three, six, 12 and 24 weeks. The distal part of each femur was removed, fixed in alcohol, embedded in methylmethacrylate, sawed to 80 microns thick for oxytetracycline (OTC)-labeling studies and microradiography, and sectioned at 5 microns for histologic studies. As judged by histologic microradiographic, and OTC-labeling studies, 19 of 24 osteotomies were healing normally; after six weeks of follow-up examination, union of 11 of 14 osteotomies was observed on radiographs. On the basis of the present study, PGA threads may be promising for the fixation of osteotomies of the metaphyseal cancellous bone in rabbits.</description><subject>Animals</subject><subject>Biodegradation, Environmental</subject><subject>Biological and medical sciences</subject><subject>Female</subject><subject>Femur - anatomy & histology</subject><subject>Femur - surgery</subject><subject>Follow-Up Studies</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Orthopedic surgery</subject><subject>Osteotomy - methods</subject><subject>Polyglycolic Acid - metabolism</subject><subject>Rabbits</subject><subject>Surgery (general aspects). Transplantations, organ and tissue grafts. 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Transplantations, organ and tissue grafts. Graft diseases</topic><topic>Suture Techniques</topic><topic>Sutures</topic><topic>Wound Healing</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>VIHTONEN, K</creatorcontrib><creatorcontrib>VAINIONPAA, S</creatorcontrib><creatorcontrib>MERO, M</creatorcontrib><creatorcontrib>PATIALA, H</creatorcontrib><creatorcontrib>ROKKANEN, P</creatorcontrib><creatorcontrib>KILPIKARI, J</creatorcontrib><creatorcontrib>TORMALA, P</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><jtitle>Clinical orthopaedics and related research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>VIHTONEN, K</au><au>VAINIONPAA, S</au><au>MERO, M</au><au>PATIALA, H</au><au>ROKKANEN, P</au><au>KILPIKARI, J</au><au>TORMALA, P</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Fixation of experimental osteotomy of the distal femur with biodegradable thread in rabbits</atitle><jtitle>Clinical orthopaedics and related research</jtitle><addtitle>Clin Orthop Relat Res</addtitle><date>1987-08-01</date><risdate>1987</risdate><volume>221</volume><issue>221</issue><spage>297</spage><epage>303</epage><pages>297-303</pages><issn>0009-921X</issn><eissn>1528-1132</eissn><coden>CORTBR</coden><abstract>A distal femoral osteotomy on 24 rabbits was fixed with biodegradable polyglycolic acid (PGA) thread pulled through drill holes made on both sides of the osteotomy. Follow-up times were one, three, six, 12 and 24 weeks. The distal part of each femur was removed, fixed in alcohol, embedded in methylmethacrylate, sawed to 80 microns thick for oxytetracycline (OTC)-labeling studies and microradiography, and sectioned at 5 microns for histologic studies. As judged by histologic microradiographic, and OTC-labeling studies, 19 of 24 osteotomies were healing normally; after six weeks of follow-up examination, union of 11 of 14 osteotomies was observed on radiographs. On the basis of the present study, PGA threads may be promising for the fixation of osteotomies of the metaphyseal cancellous bone in rabbits.</abstract><cop>Heidelberg</cop><pub>Springer</pub><pmid>3038446</pmid><doi>10.1097/00003086-198708000-00040</doi><tpages>7</tpages></addata></record> |
| fulltext | fulltext |
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| ispartof | Clinical orthopaedics and related research, 1987-08, Vol.221 (221), p.297-303 |
| issn | 0009-921X 1528-1132 |
| language | eng |
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| source | MEDLINE; Journals@Ovid Complete |
| subjects | Animals Biodegradation, Environmental Biological and medical sciences Female Femur - anatomy & histology Femur - surgery Follow-Up Studies Male Medical sciences Orthopedic surgery Osteotomy - methods Polyglycolic Acid - metabolism Rabbits Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Suture Techniques Sutures Wound Healing |
| title | Fixation of experimental osteotomy of the distal femur with biodegradable thread in rabbits |
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