Adaptations in skeletal muscle disuse or decreased-use atrophy
Those factors that seem to play some role in inducing adaptations of skeletal muscle in vivo are discussed. The role of myogenesis in maintaining and repairing muscle during atrophic and hypertrophic states is discussed, including pointing out that the modulation of myonuclear number is one means of...
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Veröffentlicht in: | American journal of physical medicine & rehabilitation 2002-11, Vol.81 (11 Suppl), p.S127-S147 |
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container_issue | 11 Suppl |
container_start_page | S127 |
container_title | American journal of physical medicine & rehabilitation |
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creator | Edgerton, V Reggie Roy, Roland R Allen, David L Monti, Ryan J |
description | Those factors that seem to play some role in inducing adaptations of skeletal muscle in vivo are discussed. The role of myogenesis in maintaining and repairing muscle during atrophic and hypertrophic states is discussed, including pointing out that the modulation of myonuclear number is one means of adapting to varying chronic levels of neuromuscular activity. Finally, we point out the potential consequences of muscle atrophy on the control of movement and the susceptibility to fatigue. |
doi_str_mv | 10.1097/00002060-200211001-00014 |
format | Article |
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The role of myogenesis in maintaining and repairing muscle during atrophic and hypertrophic states is discussed, including pointing out that the modulation of myonuclear number is one means of adapting to varying chronic levels of neuromuscular activity. Finally, we point out the potential consequences of muscle atrophy on the control of movement and the susceptibility to fatigue.</description><subject>Adaptation, Physiological</subject><subject>Animals</subject><subject>Fatigue - etiology</subject><subject>Humans</subject><subject>Muscle Development</subject><subject>Muscle, Skeletal - metabolism</subject><subject>Muscular Atrophy - metabolism</subject><subject>Phenotype</subject><issn>0894-9115</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2002</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkM1OwzAQBn0A0VJ4BeQXMOzGaRxfkKqKP6kSl96jtb0RgbSJ7OTQtyelBfbySSPNHkYIiXCPYM0DTJdBASqbFhEA1UQwvxBzKG2uLOJyJq5T-pzw0mpzJWaY5WBLLOficRWoH2houn2SzV6mL255oFbuxuRblqFJY2LZRRnYR6bEQR0BDbHrPw434rKmNvHteRdi-_y0Xb-qzfvL23q1UV7nxaCMKwq0mSZvg0fCmpzRWZ4ZbwISMzpCcqBzD4YpoCEGRzUwLgFcrReiPL31sUspcl31sdlRPFQI1bFC9Vuh-qtQ_VSY1LuT2o9ux-FfPCfQ3y-8WsQ</recordid><startdate>200211</startdate><enddate>200211</enddate><creator>Edgerton, V Reggie</creator><creator>Roy, Roland R</creator><creator>Allen, David L</creator><creator>Monti, Ryan J</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>200211</creationdate><title>Adaptations in skeletal muscle disuse or decreased-use atrophy</title><author>Edgerton, V Reggie ; Roy, Roland R ; Allen, David L ; Monti, Ryan J</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c346t-7b661923ac9dc1a1fab732427c7d1aee1ba1ab034c07ead17ae0baf0e1500bf3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2002</creationdate><topic>Adaptation, Physiological</topic><topic>Animals</topic><topic>Fatigue - etiology</topic><topic>Humans</topic><topic>Muscle Development</topic><topic>Muscle, Skeletal - metabolism</topic><topic>Muscular Atrophy - metabolism</topic><topic>Phenotype</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Edgerton, V Reggie</creatorcontrib><creatorcontrib>Roy, Roland R</creatorcontrib><creatorcontrib>Allen, David L</creatorcontrib><creatorcontrib>Monti, Ryan J</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><jtitle>American journal of physical medicine & rehabilitation</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Edgerton, V Reggie</au><au>Roy, Roland R</au><au>Allen, David L</au><au>Monti, Ryan J</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Adaptations in skeletal muscle disuse or decreased-use atrophy</atitle><jtitle>American journal of physical medicine & rehabilitation</jtitle><addtitle>Am J Phys Med Rehabil</addtitle><date>2002-11</date><risdate>2002</risdate><volume>81</volume><issue>11 Suppl</issue><spage>S127</spage><epage>S147</epage><pages>S127-S147</pages><issn>0894-9115</issn><abstract>Those factors that seem to play some role in inducing adaptations of skeletal muscle in vivo are discussed. The role of myogenesis in maintaining and repairing muscle during atrophic and hypertrophic states is discussed, including pointing out that the modulation of myonuclear number is one means of adapting to varying chronic levels of neuromuscular activity. Finally, we point out the potential consequences of muscle atrophy on the control of movement and the susceptibility to fatigue.</abstract><cop>United States</cop><pmid>12409818</pmid><doi>10.1097/00002060-200211001-00014</doi></addata></record> |
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identifier | ISSN: 0894-9115 |
ispartof | American journal of physical medicine & rehabilitation, 2002-11, Vol.81 (11 Suppl), p.S127-S147 |
issn | 0894-9115 |
language | eng |
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source | MEDLINE; Journals@Ovid Complete |
subjects | Adaptation, Physiological Animals Fatigue - etiology Humans Muscle Development Muscle, Skeletal - metabolism Muscular Atrophy - metabolism Phenotype |
title | Adaptations in skeletal muscle disuse or decreased-use atrophy |
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