Irinotecan and capecitabine as second-line treatment after failure for first-line infusional 24-h 5-fluorouracil/folinic acid in advanced colorectal cancer: a phase II study

The efficacy of combination therapy with irinotecan and capecitabine has been demonstrated for the first-line treatment of metastatic colorectal cancer (MCRC). The aim of this trial was to evaluate the efficacy and safety of this combination in MCRC as second-line treatment after failure of 24-h inf...

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Veröffentlicht in:	Anti-cancer drugs 2005-01, Vol.16 (1), p.39-45
Hauptverfasser:	Hofheinz, Ralf-Dieter, Gnad-Vogt, Ulrike, Wein, Axel, Saussele, Susanne, Kreil, Sebastian, Pilz, Lothar, Hehlmann, Rüdiger, Hochhaus, Andreas
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - drug therapy Adenocarcinoma - pathology Adult Aged Antineoplastic Combined Chemotherapy Protocols - therapeutic use Camptothecin - administration & dosage Camptothecin - analogs & derivatives Capecitabine Colorectal Neoplasms - drug therapy Colorectal Neoplasms - pathology Deoxycytidine - administration & dosage Deoxycytidine - analogs & derivatives Female Fluorouracil - administration & dosage Humans Infusions, Intravenous Leucovorin - administration & dosage Male Middle Aged Neoplasm Staging Survival Analysis Treatment Failure Treatment Outcome
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