Apoptosis-based drug screening and detection of selective toxicity to cancer cells

The goal of our study was to determine whether an apoptosis assay used after short-term drug exposure could predict selective toxicity to cancer cells. To this end we compared the effect of eight anticancer drugs and 10 toxic compounds without known antitumor activity in cultures of human breast can...

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Veröffentlicht in:	Anti-cancer drugs 2003-08, Vol.14 (7), p.555-561
Hauptverfasser:	Frankfurt, Oskar S, Krishan, Awtar
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents - therapeutic use Apoptosis - drug effects Breast Neoplasms - drug therapy Enzyme-Linked Immunosorbent Assay Humans Toxins, Biological - therapeutic use Tumor Cells, Cultured
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