15-Deoxy-Δ12,14-prostaglandin J2 induces apoptosis of a thyroid papillary cancer cell line (CG3 cells) through increasing intracellular iron and oxidative stress

Treatment of carcinoma cell lines with 15-deoxy-Δ-prostaglandin J2 (15d-PGJ2), a natural ligand of the peroxisome proliferator-activated receptor-γ, has been reported to induce apoptosis and/or inhibit proliferation. In this study, we investigated the cytotoxic effect and the action mechanisms of 15...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Anti-cancer drugs 2002-08, Vol.13 (7), p.759-765
Hauptverfasser:	Chen, Shu-Yi, Lu, Fung-Jou, Gau, Rung-Jiun, Yang, Mei-Ling, Huang, Tien-Shang
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!