Interferon-α and interferon-γ combined with chemotherapy: in vitro sensitivity studies in non-small cell lung cancer cell lines

Non-small cell lung cancers (NSCLC) are often resistant to chemotherapy. Cisplatin has shown the most activity against all the histological subtypes and is now used in most combined treatment programmes. Interferon (IFN)-α has been shown to potentiate cisplatin and other drugs experimentally and in...

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Veröffentlicht in:	Anti-cancer drugs 1993-06, Vol.4 (3), p.365-368
Hauptverfasser:	Hand, Anne, Pelin, Katarina, Halme, Maija, Ekman, Anna, Mattson, Madeleine, Vallas, Marjatta, Mattson, Karin, Linnainmaa, Kaija, Husgafvel-Pursiainen, Kirsti
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - drug therapy Antineoplastic Combined Chemotherapy Protocols - pharmacology Carcinoma, Non-Small-Cell Lung - drug therapy Cisplatin - administration & dosage Cisplatin - pharmacology Drug Screening Assays, Antitumor Drug Synergism Etoposide - administration & dosage Etoposide - pharmacology Humans Interferon Type I - administration & dosage Interferon-gamma - administration & dosage Lung Neoplasms - drug therapy Recombinant Proteins Tumor Cells, Cultured - drug effects
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