Little evidence of reduced survival to adulthood of apoE ε4 homozygotes in Downʼs syndrome

IT has been proposed that homozygosity for the apolipoprotein E (apoE) ε4 allele decreases the probability of an individual with Downʼs syndrome (DS) surviving to adulthood. We performed a meta-analysis of 11 published DS series for which apoE genotype data were available. Seven ε4 homozygotes out o...

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Veröffentlicht in:	Neuroreport 1997-11, Vol.8 (16), p.3463-3465
Hauptverfasser:	Edland, Steven D, Wijsman, Ellen M, Schoder-Ehri, Gabriel L, B. Leverenz, and James
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Chromosome aberrations Medical genetics Medical sciences
Online-Zugang:	Volltext
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