Cognitive functioning in experimental hypoglycaemia assessed with event-related potentials

COGNITIVE effects of experimentally induced hypoglycaemia were investigated by event-related brain potentials (ERPs) in auditory and visual classification tasks. In a cross-over design eight healthy male subjects (age 22–27 years) were studied under control conditions or following administration of...

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Veröffentlicht in:	Neuroreport 1995-07, Vol.6 (11), p.1509-1512
Hauptverfasser:	Münte, T F, Berger, D, Terkamp, C, Schöfl, C, Johannes, S, Brabant, G
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Behavioral psychophysiology Biological and medical sciences Cognition Disorders - chemically induced Cognition Disorders - physiopathology Cross-Over Studies Evaluation Studies as Topic Evoked Potentials, Auditory - physiology Evoked Potentials, Visual - physiology Fundamental and applied biological sciences. Psychology Humans Hypoglycemia - chemically induced Hypoglycemia - psychology Insulin Male Miscellaneous Psychology. Psychoanalysis. Psychiatry Psychology. Psychophysiology Reference Values
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Zusammenfassung:	COGNITIVE effects of experimentally induced hypoglycaemia were investigated by event-related brain potentials (ERPs) in auditory and visual classification tasks. In a cross-over design eight healthy male subjects (age 22–27 years) were studied under control conditions or following administration of 0.15 IU insulin kg. The ERPs showed preserved early cortical components, while the N2 component was greatly reduced in both modalities. P3 components did not show an influence of hypoglycemia. These results suggest that the cognitive deficits are due to an impairment of automatic feature extraction from the stimuli.
ISSN:	0959-4965 1473-558X
DOI:	10.1097/00001756-199507310-00011