Mafenide acetate allergy presenting as recurrent chondritis
Acute chondritis has a strong predilection for recurrence. Mafenide acetate has been implicated in causing reactions that mimic this condition; however, these hypersensitivity reactions lack fever, fluctuance, and pain. The authors report a case of mafenide acetate allergy presenting as recurrent ch...
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| Veröffentlicht in: | Annals of plastic surgery 2002-02, Vol.48 (2), p.202-204 |
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| container_end_page | 204 |
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| container_title | Annals of plastic surgery |
| container_volume | 48 |
| creator | PICKUS, Evan J LIONELLI, Gerald T WOODALL, Charles E KORENTAGER, Richard A |
| description | Acute chondritis has a strong predilection for recurrence. Mafenide acetate has been implicated in causing reactions that mimic this condition; however, these hypersensitivity reactions lack fever, fluctuance, and pain. The authors report a case of mafenide acetate allergy presenting as recurrent chondritis in a patient who had previously been treated successfully for this condition. In this patient, the allergic response resolved within 3 days after cessation of mafenide acetate. If unappreciated, it may have led to unnecessary operative intervention. Therefore, auricular edema and erythema, without fever, fluctuance, and pain, must be recognized by surgeons as a possible mafenide acetate allergy and must be considered in the differential diagnosis for patients who present with recurrent acute suppurative chondritis. |
| doi_str_mv | 10.1097/00000637-200202000-00016 |
| format | Article |
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Mafenide acetate has been implicated in causing reactions that mimic this condition; however, these hypersensitivity reactions lack fever, fluctuance, and pain. The authors report a case of mafenide acetate allergy presenting as recurrent chondritis in a patient who had previously been treated successfully for this condition. In this patient, the allergic response resolved within 3 days after cessation of mafenide acetate. If unappreciated, it may have led to unnecessary operative intervention. Therefore, auricular edema and erythema, without fever, fluctuance, and pain, must be recognized by surgeons as a possible mafenide acetate allergy and must be considered in the differential diagnosis for patients who present with recurrent acute suppurative chondritis.</description><identifier>ISSN: 0148-7043</identifier><identifier>EISSN: 1536-3708</identifier><identifier>DOI: 10.1097/00000637-200202000-00016</identifier><identifier>PMID: 11910229</identifier><identifier>CODEN: APCSD4</identifier><language>eng</language><publisher>Hagerstown, MD: Lippincott Williams & Wilkins</publisher><subject>Adult ; Anti-Infective Agents, Local - adverse effects ; Anti-Infective Agents, Local - therapeutic use ; Biological and medical sciences ; Burns - drug therapy ; Diagnosis, Differential ; Drug Hypersensitivity - diagnosis ; Drug Hypersensitivity - etiology ; Drug Hypersensitivity - therapy ; Drug toxicity and drugs side effects treatment ; Ear, External - injuries ; Humans ; Mafenide - adverse effects ; Mafenide - therapeutic use ; Male ; Medical sciences ; Miscellaneous (drug allergy, mutagens, teratogens...) ; Osteochondritis - diagnosis ; Osteochondritis - etiology ; Osteochondritis - therapy ; Otitis Externa - diagnosis ; Otitis Externa - etiology ; Otitis Externa - therapy ; Pharmacology. 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Mafenide acetate has been implicated in causing reactions that mimic this condition; however, these hypersensitivity reactions lack fever, fluctuance, and pain. The authors report a case of mafenide acetate allergy presenting as recurrent chondritis in a patient who had previously been treated successfully for this condition. In this patient, the allergic response resolved within 3 days after cessation of mafenide acetate. If unappreciated, it may have led to unnecessary operative intervention. Therefore, auricular edema and erythema, without fever, fluctuance, and pain, must be recognized by surgeons as a possible mafenide acetate allergy and must be considered in the differential diagnosis for patients who present with recurrent acute suppurative chondritis.</description><subject>Adult</subject><subject>Anti-Infective Agents, Local - adverse effects</subject><subject>Anti-Infective Agents, Local - therapeutic use</subject><subject>Biological and medical sciences</subject><subject>Burns - drug therapy</subject><subject>Diagnosis, Differential</subject><subject>Drug Hypersensitivity - diagnosis</subject><subject>Drug Hypersensitivity - etiology</subject><subject>Drug Hypersensitivity - therapy</subject><subject>Drug toxicity and drugs side effects treatment</subject><subject>Ear, External - injuries</subject><subject>Humans</subject><subject>Mafenide - adverse effects</subject><subject>Mafenide - therapeutic use</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Miscellaneous (drug allergy, mutagens, teratogens...)</subject><subject>Osteochondritis - diagnosis</subject><subject>Osteochondritis - etiology</subject><subject>Osteochondritis - therapy</subject><subject>Otitis Externa - diagnosis</subject><subject>Otitis Externa - etiology</subject><subject>Otitis Externa - therapy</subject><subject>Pharmacology. 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Drug treatments</topic><topic>Recurrence</topic><topic>Tars - adverse effects</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>PICKUS, Evan J</creatorcontrib><creatorcontrib>LIONELLI, Gerald T</creatorcontrib><creatorcontrib>WOODALL, Charles E</creatorcontrib><creatorcontrib>KORENTAGER, Richard A</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><jtitle>Annals of plastic surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>PICKUS, Evan J</au><au>LIONELLI, Gerald T</au><au>WOODALL, Charles E</au><au>KORENTAGER, Richard A</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Mafenide acetate allergy presenting as recurrent chondritis</atitle><jtitle>Annals of plastic surgery</jtitle><addtitle>Ann Plast Surg</addtitle><date>2002-02-01</date><risdate>2002</risdate><volume>48</volume><issue>2</issue><spage>202</spage><epage>204</epage><pages>202-204</pages><issn>0148-7043</issn><eissn>1536-3708</eissn><coden>APCSD4</coden><abstract>Acute chondritis has a strong predilection for recurrence. Mafenide acetate has been implicated in causing reactions that mimic this condition; however, these hypersensitivity reactions lack fever, fluctuance, and pain. The authors report a case of mafenide acetate allergy presenting as recurrent chondritis in a patient who had previously been treated successfully for this condition. In this patient, the allergic response resolved within 3 days after cessation of mafenide acetate. If unappreciated, it may have led to unnecessary operative intervention. Therefore, auricular edema and erythema, without fever, fluctuance, and pain, must be recognized by surgeons as a possible mafenide acetate allergy and must be considered in the differential diagnosis for patients who present with recurrent acute suppurative chondritis.</abstract><cop>Hagerstown, MD</cop><pub>Lippincott Williams & Wilkins</pub><pmid>11910229</pmid><doi>10.1097/00000637-200202000-00016</doi><tpages>3</tpages></addata></record> |
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| ispartof | Annals of plastic surgery, 2002-02, Vol.48 (2), p.202-204 |
| issn | 0148-7043 1536-3708 |
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| source | MEDLINE; Journals@Ovid Complete |
| subjects | Adult Anti-Infective Agents, Local - adverse effects Anti-Infective Agents, Local - therapeutic use Biological and medical sciences Burns - drug therapy Diagnosis, Differential Drug Hypersensitivity - diagnosis Drug Hypersensitivity - etiology Drug Hypersensitivity - therapy Drug toxicity and drugs side effects treatment Ear, External - injuries Humans Mafenide - adverse effects Mafenide - therapeutic use Male Medical sciences Miscellaneous (drug allergy, mutagens, teratogens...) Osteochondritis - diagnosis Osteochondritis - etiology Osteochondritis - therapy Otitis Externa - diagnosis Otitis Externa - etiology Otitis Externa - therapy Pharmacology. Drug treatments Recurrence Tars - adverse effects Treatment Outcome |
| title | Mafenide acetate allergy presenting as recurrent chondritis |
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