Analysis of silicon in human breast and capsular tissue surrounding prostheses and expanders
Diffusion of polydimethylsiloxane from silicone breast prostheses and soft-tissue expanders has been associated with capsular contraction. We used electron dispersive x-ray analysis and scanning electron microscopy to assess the presence of silicon in capsular tissue surrounding three categories of...
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| Veröffentlicht in: | Annals of plastic surgery 1991-12, Vol.27 (6), p.553-558 |
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| container_end_page | 558 |
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| container_issue | 6 |
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| container_title | Annals of plastic surgery |
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| creator | JENNINGS, D. A MORYKWAS, M. J DE FRANZO, A. J ARGENTO, L. C |
| description | Diffusion of polydimethylsiloxane from silicone breast prostheses and soft-tissue expanders has been associated with capsular contraction. We used electron dispersive x-ray analysis and scanning electron microscopy to assess the presence of silicon in capsular tissue surrounding three categories of breast prostheses and expanders. Breast and subcutaneous tissues external to the capsules were used as control specimens. Semiquantitative results allowed capsules to be ranked according to implant type. Silicon was localized within the inner 2.0 mm of capsular tissue. The analyses of tissues from 2 patients exhibiting unilateral, Baker grade IV contraction after bilateral placement of prostheses showed less silicon present in the severely contracted capsule than in the less-contracted capsule. Results from this study diminish the importance of silicon as the initiator of capsular contraction. |
| doi_str_mv | 10.1097/00000637-199112000-00007 |
| format | Article |
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A ; MORYKWAS, M. J ; DE FRANZO, A. J ; ARGENTO, L. C</creator><creatorcontrib>JENNINGS, D. A ; MORYKWAS, M. J ; DE FRANZO, A. J ; ARGENTO, L. C</creatorcontrib><description>Diffusion of polydimethylsiloxane from silicone breast prostheses and soft-tissue expanders has been associated with capsular contraction. We used electron dispersive x-ray analysis and scanning electron microscopy to assess the presence of silicon in capsular tissue surrounding three categories of breast prostheses and expanders. Breast and subcutaneous tissues external to the capsules were used as control specimens. Semiquantitative results allowed capsules to be ranked according to implant type. Silicon was localized within the inner 2.0 mm of capsular tissue. The analyses of tissues from 2 patients exhibiting unilateral, Baker grade IV contraction after bilateral placement of prostheses showed less silicon present in the severely contracted capsule than in the less-contracted capsule. Results from this study diminish the importance of silicon as the initiator of capsular contraction.</description><identifier>ISSN: 0148-7043</identifier><identifier>EISSN: 1536-3708</identifier><identifier>DOI: 10.1097/00000637-199112000-00007</identifier><identifier>PMID: 1793241</identifier><identifier>CODEN: APCSD4</identifier><language>eng</language><publisher>Hagerstown, MD: Lippincott Williams & Wilkins</publisher><subject>Biological and medical sciences ; Breast Diseases - chemically induced ; Breast Diseases - pathology ; Breast Diseases - surgery ; Dimethylpolysiloxanes - adverse effects ; Dimethylpolysiloxanes - analysis ; Electron Probe Microanalysis ; Evaluation Studies as Topic ; Female ; Humans ; Medical sciences ; Microscopy, Electron, Scanning ; Postoperative Complications - chemically induced ; Postoperative Complications - pathology ; Postoperative Complications - surgery ; Prostheses and Implants - adverse effects ; Prosthesis Failure ; Skin plastic surgery ; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases ; Time Factors</subject><ispartof>Annals of plastic surgery, 1991-12, Vol.27 (6), p.553-558</ispartof><rights>1992 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c339t-9e98047549eb2cf4f52a12df981de17eb0e9ff3bbd7a804c9b819e983a41a1563</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,777,781,27905,27906</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=5393119$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/1793241$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>JENNINGS, D. A</creatorcontrib><creatorcontrib>MORYKWAS, M. J</creatorcontrib><creatorcontrib>DE FRANZO, A. J</creatorcontrib><creatorcontrib>ARGENTO, L. C</creatorcontrib><title>Analysis of silicon in human breast and capsular tissue surrounding prostheses and expanders</title><title>Annals of plastic surgery</title><addtitle>Ann Plast Surg</addtitle><description>Diffusion of polydimethylsiloxane from silicone breast prostheses and soft-tissue expanders has been associated with capsular contraction. We used electron dispersive x-ray analysis and scanning electron microscopy to assess the presence of silicon in capsular tissue surrounding three categories of breast prostheses and expanders. Breast and subcutaneous tissues external to the capsules were used as control specimens. Semiquantitative results allowed capsules to be ranked according to implant type. Silicon was localized within the inner 2.0 mm of capsular tissue. The analyses of tissues from 2 patients exhibiting unilateral, Baker grade IV contraction after bilateral placement of prostheses showed less silicon present in the severely contracted capsule than in the less-contracted capsule. Results from this study diminish the importance of silicon as the initiator of capsular contraction.</description><subject>Biological and medical sciences</subject><subject>Breast Diseases - chemically induced</subject><subject>Breast Diseases - pathology</subject><subject>Breast Diseases - surgery</subject><subject>Dimethylpolysiloxanes - adverse effects</subject><subject>Dimethylpolysiloxanes - analysis</subject><subject>Electron Probe Microanalysis</subject><subject>Evaluation Studies as Topic</subject><subject>Female</subject><subject>Humans</subject><subject>Medical sciences</subject><subject>Microscopy, Electron, Scanning</subject><subject>Postoperative Complications - chemically induced</subject><subject>Postoperative Complications - pathology</subject><subject>Postoperative Complications - surgery</subject><subject>Prostheses and Implants - adverse effects</subject><subject>Prosthesis Failure</subject><subject>Skin plastic surgery</subject><subject>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</subject><subject>Time Factors</subject><issn>0148-7043</issn><issn>1536-3708</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1991</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFUF1LwzAUDaLMOf0JQh58reY2adM8juEXDHzRN6GkaeIiXVpyW3D_3nab874c7vm4XA4hFNg9MCUf2DQ5lwkoBZCOSzIx8ozMIeN5wiUrzsmcgSgSyQS_JFeI34xBWoh8RmYgFU8FzMnnMuhmhx5p6yj6xps2UB_oZtjqQKtoNfZUh5oa3eHQ6Eh7jzhYikOM7RBqH75oF1vsNxYt7q32pxvBRrwmF043aG-OuCAfT4_vq5dk_fb8ulquE8O56hNlVcGEzISyVWqccFmqIa2dKqC2IG3FrHKOV1Ut9Wg0qipgynAtQEOW8wUpDnfN-AhG68ou-q2OuxJYOfVV_vVVnvraU3KM3h6i3VBtbf0fPBQ06ndHXaPRjYs6GI8nW8YVB1D8FwPHdCo</recordid><startdate>19911201</startdate><enddate>19911201</enddate><creator>JENNINGS, D. A</creator><creator>MORYKWAS, M. J</creator><creator>DE FRANZO, A. J</creator><creator>ARGENTO, L. C</creator><general>Lippincott Williams & Wilkins</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>19911201</creationdate><title>Analysis of silicon in human breast and capsular tissue surrounding prostheses and expanders</title><author>JENNINGS, D. A ; MORYKWAS, M. J ; DE FRANZO, A. J ; ARGENTO, L. C</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c339t-9e98047549eb2cf4f52a12df981de17eb0e9ff3bbd7a804c9b819e983a41a1563</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1991</creationdate><topic>Biological and medical sciences</topic><topic>Breast Diseases - chemically induced</topic><topic>Breast Diseases - pathology</topic><topic>Breast Diseases - surgery</topic><topic>Dimethylpolysiloxanes - adverse effects</topic><topic>Dimethylpolysiloxanes - analysis</topic><topic>Electron Probe Microanalysis</topic><topic>Evaluation Studies as Topic</topic><topic>Female</topic><topic>Humans</topic><topic>Medical sciences</topic><topic>Microscopy, Electron, Scanning</topic><topic>Postoperative Complications - chemically induced</topic><topic>Postoperative Complications - pathology</topic><topic>Postoperative Complications - surgery</topic><topic>Prostheses and Implants - adverse effects</topic><topic>Prosthesis Failure</topic><topic>Skin plastic surgery</topic><topic>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</topic><topic>Time Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>JENNINGS, D. A</creatorcontrib><creatorcontrib>MORYKWAS, M. J</creatorcontrib><creatorcontrib>DE FRANZO, A. J</creatorcontrib><creatorcontrib>ARGENTO, L. C</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><jtitle>Annals of plastic surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>JENNINGS, D. A</au><au>MORYKWAS, M. J</au><au>DE FRANZO, A. J</au><au>ARGENTO, L. C</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Analysis of silicon in human breast and capsular tissue surrounding prostheses and expanders</atitle><jtitle>Annals of plastic surgery</jtitle><addtitle>Ann Plast Surg</addtitle><date>1991-12-01</date><risdate>1991</risdate><volume>27</volume><issue>6</issue><spage>553</spage><epage>558</epage><pages>553-558</pages><issn>0148-7043</issn><eissn>1536-3708</eissn><coden>APCSD4</coden><abstract>Diffusion of polydimethylsiloxane from silicone breast prostheses and soft-tissue expanders has been associated with capsular contraction. We used electron dispersive x-ray analysis and scanning electron microscopy to assess the presence of silicon in capsular tissue surrounding three categories of breast prostheses and expanders. Breast and subcutaneous tissues external to the capsules were used as control specimens. Semiquantitative results allowed capsules to be ranked according to implant type. Silicon was localized within the inner 2.0 mm of capsular tissue. The analyses of tissues from 2 patients exhibiting unilateral, Baker grade IV contraction after bilateral placement of prostheses showed less silicon present in the severely contracted capsule than in the less-contracted capsule. Results from this study diminish the importance of silicon as the initiator of capsular contraction.</abstract><cop>Hagerstown, MD</cop><pub>Lippincott Williams & Wilkins</pub><pmid>1793241</pmid><doi>10.1097/00000637-199112000-00007</doi><tpages>6</tpages></addata></record> |
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| identifier | ISSN: 0148-7043 |
| ispartof | Annals of plastic surgery, 1991-12, Vol.27 (6), p.553-558 |
| issn | 0148-7043 1536-3708 |
| language | eng |
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| source | MEDLINE; Journals@Ovid Complete |
| subjects | Biological and medical sciences Breast Diseases - chemically induced Breast Diseases - pathology Breast Diseases - surgery Dimethylpolysiloxanes - adverse effects Dimethylpolysiloxanes - analysis Electron Probe Microanalysis Evaluation Studies as Topic Female Humans Medical sciences Microscopy, Electron, Scanning Postoperative Complications - chemically induced Postoperative Complications - pathology Postoperative Complications - surgery Prostheses and Implants - adverse effects Prosthesis Failure Skin plastic surgery Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Time Factors |
| title | Analysis of silicon in human breast and capsular tissue surrounding prostheses and expanders |
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