Efficacy of postoperative patient-controlled and continuous infusion epidural analgesia versus intravenous patient-controlled analgesia with opioids : A meta-analysis
The authors performed a meta-analysis and found that epidural analgesia overall provided superior postoperative analgesia compared with intravenous patient-controlled analgesia. For all types of surgery and pain assessments, all forms of epidural analgesia (both continuous epidural infusion and pati...
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Veröffentlicht in: | Anesthesiology (Philadelphia) 2005-11, Vol.103 (5), p.1079-1088 |
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creator | WU, Christopher L COHEN, Seth R RICHMAN, Jeffrey M ROWLINGSON, Andrew J COURPAS, Genevieve E CHEUNG, Kristin LIN, Elaina E LIU, Spencer S |
description | The authors performed a meta-analysis and found that epidural analgesia overall provided superior postoperative analgesia compared with intravenous patient-controlled analgesia. For all types of surgery and pain assessments, all forms of epidural analgesia (both continuous epidural infusion and patient-controlled epidural analgesia) provided significantly superior postoperative analgesia compared with intravenous patient-controlled analgesia, with the exception of hydrophilic opioid-only epidural regimens. Continuous epidural infusion provided statistically significantly superior analgesia versus patient-controlled epidural analgesia for overall pain, pain at rest, and pain with activity; however, patients receiving continuous epidural infusion had a significantly higher incidence of nausea-vomiting and motor block but lower incidence of pruritus. In summary, almost without exception, epidural analgesia, regardless of analgesic agent, epidural regimen, and type and time of pain assessment, provided superior postoperative analgesia compared to intravenous patient-controlled analgesia. |
doi_str_mv | 10.1097/00000542-200511000-00023 |
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For all types of surgery and pain assessments, all forms of epidural analgesia (both continuous epidural infusion and patient-controlled epidural analgesia) provided significantly superior postoperative analgesia compared with intravenous patient-controlled analgesia, with the exception of hydrophilic opioid-only epidural regimens. Continuous epidural infusion provided statistically significantly superior analgesia versus patient-controlled epidural analgesia for overall pain, pain at rest, and pain with activity; however, patients receiving continuous epidural infusion had a significantly higher incidence of nausea-vomiting and motor block but lower incidence of pruritus. In summary, almost without exception, epidural analgesia, regardless of analgesic agent, epidural regimen, and type and time of pain assessment, provided superior postoperative analgesia compared to intravenous patient-controlled analgesia.</description><identifier>ISSN: 0003-3022</identifier><identifier>EISSN: 1528-1175</identifier><identifier>DOI: 10.1097/00000542-200511000-00023</identifier><identifier>PMID: 16249683</identifier><identifier>CODEN: ANESAV</identifier><language>eng</language><publisher>Hagerstown, MD: Lippincott</publisher><subject>Analgesia, Epidural ; Analgesia, Patient-Controlled ; Analgesics, Opioid - administration & dosage ; Analgesics, Opioid - adverse effects ; Analgesics, Opioid - therapeutic use ; Anesthesia ; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy ; Biological and medical sciences ; Humans ; Infusions, Intravenous ; Medical sciences ; Pain Measurement ; Pain, Postoperative - drug therapy</subject><ispartof>Anesthesiology (Philadelphia), 2005-11, Vol.103 (5), p.1079-1088</ispartof><rights>2005 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=17234202$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16249683$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>WU, Christopher L</creatorcontrib><creatorcontrib>COHEN, Seth R</creatorcontrib><creatorcontrib>RICHMAN, Jeffrey M</creatorcontrib><creatorcontrib>ROWLINGSON, Andrew J</creatorcontrib><creatorcontrib>COURPAS, Genevieve E</creatorcontrib><creatorcontrib>CHEUNG, Kristin</creatorcontrib><creatorcontrib>LIN, Elaina E</creatorcontrib><creatorcontrib>LIU, Spencer S</creatorcontrib><title>Efficacy of postoperative patient-controlled and continuous infusion epidural analgesia versus intravenous patient-controlled analgesia with opioids : A meta-analysis</title><title>Anesthesiology (Philadelphia)</title><addtitle>Anesthesiology</addtitle><description>The authors performed a meta-analysis and found that epidural analgesia overall provided superior postoperative analgesia compared with intravenous patient-controlled analgesia. For all types of surgery and pain assessments, all forms of epidural analgesia (both continuous epidural infusion and patient-controlled epidural analgesia) provided significantly superior postoperative analgesia compared with intravenous patient-controlled analgesia, with the exception of hydrophilic opioid-only epidural regimens. Continuous epidural infusion provided statistically significantly superior analgesia versus patient-controlled epidural analgesia for overall pain, pain at rest, and pain with activity; however, patients receiving continuous epidural infusion had a significantly higher incidence of nausea-vomiting and motor block but lower incidence of pruritus. In summary, almost without exception, epidural analgesia, regardless of analgesic agent, epidural regimen, and type and time of pain assessment, provided superior postoperative analgesia compared to intravenous patient-controlled analgesia.</description><subject>Analgesia, Epidural</subject><subject>Analgesia, Patient-Controlled</subject><subject>Analgesics, Opioid - administration & dosage</subject><subject>Analgesics, Opioid - adverse effects</subject><subject>Analgesics, Opioid - therapeutic use</subject><subject>Anesthesia</subject><subject>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</subject><subject>Biological and medical sciences</subject><subject>Humans</subject><subject>Infusions, Intravenous</subject><subject>Medical sciences</subject><subject>Pain Measurement</subject><subject>Pain, Postoperative - drug therapy</subject><issn>0003-3022</issn><issn>1528-1175</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNptkEtPxCAAhInRuOvqXzBcPKI82kK9bTbrI9nEi54bSkExXWigXbN_yN8p3YdeJCGTgW_mMABAgm8JLvkdHk-eUUSTEJIMSpeyEzAlORWIEJ6fgml6Y4hhSifgIsbPZHnOxDmYkIJmZSHYFHwvjbFKqi30BnY-9r7TQfZ2o2GXRLseKe_64NtWN1C6Bo7WusEPEVpnhmi9g7qzzRBkmwDZvutoJdzoEHdIH-RGuxH_t_DIf9n-A_rOettEeA_ncK17icb_bbTxEpwZ2UZ9ddAZeHtYvi6e0Orl8XkxXyFFhegRJ7ihpaFYUKZyUuSFpqxkpcmzjGmusGJElZyTOsME16xmusywETQrOCkYYTMg9r0q-BiDNlUX7FqGbUVwNU5fHaevfqevdtOn6PU-2g31Wjd_wcPWCbg5ADIq2ZognbLxj-OUZTQ1_QBLmo8t</recordid><startdate>20051101</startdate><enddate>20051101</enddate><creator>WU, Christopher L</creator><creator>COHEN, Seth R</creator><creator>RICHMAN, Jeffrey M</creator><creator>ROWLINGSON, Andrew J</creator><creator>COURPAS, Genevieve E</creator><creator>CHEUNG, Kristin</creator><creator>LIN, Elaina E</creator><creator>LIU, Spencer S</creator><general>Lippincott</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>20051101</creationdate><title>Efficacy of postoperative patient-controlled and continuous infusion epidural analgesia versus intravenous patient-controlled analgesia with opioids : A meta-analysis</title><author>WU, Christopher L ; COHEN, Seth R ; RICHMAN, Jeffrey M ; ROWLINGSON, Andrew J ; COURPAS, Genevieve E ; CHEUNG, Kristin ; LIN, Elaina E ; LIU, Spencer S</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c288t-710d29f20823c51656e23939f5443e7c0c31c9771b4010b3b3e940f8246716313</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>Analgesia, Epidural</topic><topic>Analgesia, Patient-Controlled</topic><topic>Analgesics, Opioid - administration & dosage</topic><topic>Analgesics, Opioid - adverse effects</topic><topic>Analgesics, Opioid - therapeutic use</topic><topic>Anesthesia</topic><topic>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</topic><topic>Biological and medical sciences</topic><topic>Humans</topic><topic>Infusions, Intravenous</topic><topic>Medical sciences</topic><topic>Pain Measurement</topic><topic>Pain, Postoperative - drug therapy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>WU, Christopher L</creatorcontrib><creatorcontrib>COHEN, Seth R</creatorcontrib><creatorcontrib>RICHMAN, Jeffrey M</creatorcontrib><creatorcontrib>ROWLINGSON, Andrew J</creatorcontrib><creatorcontrib>COURPAS, Genevieve E</creatorcontrib><creatorcontrib>CHEUNG, Kristin</creatorcontrib><creatorcontrib>LIN, Elaina E</creatorcontrib><creatorcontrib>LIU, Spencer S</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><jtitle>Anesthesiology (Philadelphia)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>WU, Christopher L</au><au>COHEN, Seth R</au><au>RICHMAN, Jeffrey M</au><au>ROWLINGSON, Andrew J</au><au>COURPAS, Genevieve E</au><au>CHEUNG, Kristin</au><au>LIN, Elaina E</au><au>LIU, Spencer S</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Efficacy of postoperative patient-controlled and continuous infusion epidural analgesia versus intravenous patient-controlled analgesia with opioids : A meta-analysis</atitle><jtitle>Anesthesiology (Philadelphia)</jtitle><addtitle>Anesthesiology</addtitle><date>2005-11-01</date><risdate>2005</risdate><volume>103</volume><issue>5</issue><spage>1079</spage><epage>1088</epage><pages>1079-1088</pages><issn>0003-3022</issn><eissn>1528-1175</eissn><coden>ANESAV</coden><abstract>The authors performed a meta-analysis and found that epidural analgesia overall provided superior postoperative analgesia compared with intravenous patient-controlled analgesia. For all types of surgery and pain assessments, all forms of epidural analgesia (both continuous epidural infusion and patient-controlled epidural analgesia) provided significantly superior postoperative analgesia compared with intravenous patient-controlled analgesia, with the exception of hydrophilic opioid-only epidural regimens. Continuous epidural infusion provided statistically significantly superior analgesia versus patient-controlled epidural analgesia for overall pain, pain at rest, and pain with activity; however, patients receiving continuous epidural infusion had a significantly higher incidence of nausea-vomiting and motor block but lower incidence of pruritus. In summary, almost without exception, epidural analgesia, regardless of analgesic agent, epidural regimen, and type and time of pain assessment, provided superior postoperative analgesia compared to intravenous patient-controlled analgesia.</abstract><cop>Hagerstown, MD</cop><pub>Lippincott</pub><pmid>16249683</pmid><doi>10.1097/00000542-200511000-00023</doi><tpages>10</tpages></addata></record> |
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subjects | Analgesia, Epidural Analgesia, Patient-Controlled Analgesics, Opioid - administration & dosage Analgesics, Opioid - adverse effects Analgesics, Opioid - therapeutic use Anesthesia Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Biological and medical sciences Humans Infusions, Intravenous Medical sciences Pain Measurement Pain, Postoperative - drug therapy |
title | Efficacy of postoperative patient-controlled and continuous infusion epidural analgesia versus intravenous patient-controlled analgesia with opioids : A meta-analysis |
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