Efficacy of postoperative patient-controlled and continuous infusion epidural analgesia versus intravenous patient-controlled analgesia with opioids : A meta-analysis

The authors performed a meta-analysis and found that epidural analgesia overall provided superior postoperative analgesia compared with intravenous patient-controlled analgesia. For all types of surgery and pain assessments, all forms of epidural analgesia (both continuous epidural infusion and pati...

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Veröffentlicht in:Anesthesiology (Philadelphia) 2005-11, Vol.103 (5), p.1079-1088
Hauptverfasser: WU, Christopher L, COHEN, Seth R, RICHMAN, Jeffrey M, ROWLINGSON, Andrew J, COURPAS, Genevieve E, CHEUNG, Kristin, LIN, Elaina E, LIU, Spencer S
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container_end_page 1088
container_issue 5
container_start_page 1079
container_title Anesthesiology (Philadelphia)
container_volume 103
creator WU, Christopher L
COHEN, Seth R
RICHMAN, Jeffrey M
ROWLINGSON, Andrew J
COURPAS, Genevieve E
CHEUNG, Kristin
LIN, Elaina E
LIU, Spencer S
description The authors performed a meta-analysis and found that epidural analgesia overall provided superior postoperative analgesia compared with intravenous patient-controlled analgesia. For all types of surgery and pain assessments, all forms of epidural analgesia (both continuous epidural infusion and patient-controlled epidural analgesia) provided significantly superior postoperative analgesia compared with intravenous patient-controlled analgesia, with the exception of hydrophilic opioid-only epidural regimens. Continuous epidural infusion provided statistically significantly superior analgesia versus patient-controlled epidural analgesia for overall pain, pain at rest, and pain with activity; however, patients receiving continuous epidural infusion had a significantly higher incidence of nausea-vomiting and motor block but lower incidence of pruritus. In summary, almost without exception, epidural analgesia, regardless of analgesic agent, epidural regimen, and type and time of pain assessment, provided superior postoperative analgesia compared to intravenous patient-controlled analgesia.
doi_str_mv 10.1097/00000542-200511000-00023
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source MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Journals@Ovid Complete
subjects Analgesia, Epidural
Analgesia, Patient-Controlled
Analgesics, Opioid - administration & dosage
Analgesics, Opioid - adverse effects
Analgesics, Opioid - therapeutic use
Anesthesia
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Biological and medical sciences
Humans
Infusions, Intravenous
Medical sciences
Pain Measurement
Pain, Postoperative - drug therapy
title Efficacy of postoperative patient-controlled and continuous infusion epidural analgesia versus intravenous patient-controlled analgesia with opioids : A meta-analysis
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