Inhaled anesthetic enhancement of amyloid-β oligomerization and cytotoxicity

The majority of surgical patients receive inhaled anesthetics, principally small haloalkanes and haloethers. Long-term cognitive problems occur in the elderly subsequent to anesthesia and surgery, and previous surgery might also be a risk factor for neurodegenerative disorders like Alzheimer and Par...

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Veröffentlicht in:	Anesthesiology (Philadelphia) 2004-09, Vol.101 (3), p.703-709
Hauptverfasser:	ECKENHOFF, Roderic G, JOHANSSON, Jonas S, HUAFENG WEI, CARNINI, Anna, KANG, Baobin, WENLIN WEI, PIDIKITI, Ravindernath, KELLER, Jason M, ECKENHOFF, Maryellen F
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenal Gland Neoplasms - metabolism Adrenal Gland Neoplasms - pathology Adrenal Gland Neoplasms - ultrastructure Amyloid beta-Peptides - chemistry Amyloid beta-Peptides - metabolism Amyloid beta-Peptides - toxicity Anesthesia Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Anesthetics, Inhalation - pharmacology Animals Biological and medical sciences Central Nervous System Depressants - pharmacology Chromatography, Gel Ethanol - pharmacology Fluorescent Dyes Halothane - pharmacology Image Processing, Computer-Assisted Isoflurane - pharmacology Kinetics L-Lactate Dehydrogenase - metabolism Medical sciences Microscopy, Electron Oligopeptides - chemistry Oligopeptides - metabolism Oligopeptides - toxicity Pheochromocytoma - metabolism Pheochromocytoma - pathology Pheochromocytoma - ultrastructure Propofol - pharmacology Rats Tumor Cells, Cultured
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