The Effects of Heparin, Protamine, and Heparin/Protamine Reversal on Platelet Function Under Conditions of Arterial Shear Stress

Platelet dysfunction contributes to blood loss after cardiopulmonary bypass. This study examined the antiplatelet effects of heparin, protamine, and varying heparin/protamine ratios in an in vitro physiologic model and further elucidated the mechanism of the antiplatelet and anticoagulant effects of...

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Veröffentlicht in:	Anesthesia and analgesia 2001-07, Vol.93 (1), p.20-27
Hauptverfasser:	Griffin, Michael J., Rinder, Henry M., Smith, Brian R., Tracey, Jayne B., Kriz, Nancy S., Li, Conan K., Rinder, Christine S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Atrial Fibrillation - diagnostic imaging Atrial Fibrillation - etiology Biological and medical sciences Coronary Artery Bypass - adverse effects Drug toxicity and drugs side effects treatment Echocardiography, Transesophageal Female Heart Atria - diagnostic imaging Humans Male Medical sciences Middle Aged Mitral Valve - diagnostic imaging Monitoring, Physiologic Pharmacology. Drug treatments Postoperative Complications - diagnostic imaging Postoperative Complications - etiology Pulmonary Veins - diagnostic imaging Telemetry Toxicity: blood
Online-Zugang:	Volltext
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