Altered β Adrenergic Receptor Function in Subjects with Symptomatic Mitral Valve Prolapse

Individuals with mitral valve prolapse (MVP) frequently show symptoms of a hyperadrenergic state.βadrenergic receptor characteristics were compared in the lymphocytes of subjects with symptomatic MVP and control subjects during rest and exercise. At rest, the proportion of receptors binding agonist...

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Veröffentlicht in:	The American journal of the medical sciences 1991-08, Vol.302 (2), p.89-97
Hauptverfasser:	Anwar, Azam, Kohn, Sarah R., Dunn, James F., Hymer, Tazuko K., Kennedy, Gemma T., Crawford, Michael H., O'Rourke, Robert A., Katz, Michael S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenylate cyclase Adult Biological and medical sciences Cardiology. Vascular system Catecholamines - blood Cyclic AMP - metabolism Female Guanine nucleotide-binding protein Guanylyl Imidodiphosphate - pharmacology Heart Heart Rate - drug effects Humans Isoproterenol Isoproterenol - pharmacology Lymphocyte Lymphocytes - metabolism Medical sciences Mitral valve prolapse Mitral Valve Prolapse - physiopathology Physical Exertion Pindolol - metabolism Receptors, Adrenergic, beta - physiology β adrenergic receptor
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