Sequential administration of thymidine, 5-fluorouracil, and PALA: a phase I-II study

Twenty-seven patients with colorectal adenocarcinoma, (12) non-small cell bronchogenic carcinoma, (11) gastric adenocarcinoma (3), and adenocarcinoma of unknown primary lesion (1) were treated with the combination of thymidine (TdR), 5-fluorouracil (FU), and N-phosphonacetyl-L-aspartic acid (PALA)....

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Veröffentlicht in:	American journal of clinical oncology 1985-08, Vol.8 (4), p.332-335
Hauptverfasser:	CHIUTEN, D. F, VALDIVIESO, M, BEDIKIAN, A, BENVENUTO, J. A, MILLER, A, TI LI LOO, BODEY, G. P, FREIREICH, E. J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - drug therapy Adult Aged Antineoplastic agents Antineoplastic Combined Chemotherapy Protocols Aspartic Acid - administration & dosage Aspartic Acid - analogs & derivatives Aspartic Acid - metabolism Aspartic Acid - therapeutic use Biological and medical sciences Carcinoma, Bronchogenic - drug therapy Chemotherapy Chromatography, High Pressure Liquid Colonic Neoplasms - drug therapy Drug Administration Schedule Drug Evaluation Fluorouracil - administration & dosage Fluorouracil - metabolism Fluorouracil - therapeutic use Half-Life Humans Infusions, Parenteral Medical sciences Middle Aged Organophosphorus Compounds - therapeutic use Pharmacology. Drug treatments Phosphonoacetic Acid - administration & dosage Phosphonoacetic Acid - analogs & derivatives Phosphonoacetic Acid - metabolism Phosphonoacetic Acid - therapeutic use Stomach Neoplasms - drug therapy Thymidine - administration & dosage Thymidine - metabolism Thymidine - therapeutic use
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