Reconstructive surgery for the complications of pelvic irradiation
Severe damage to the pelvic viscera is a complication of irradiation therapy that, unfortunately, cannot always be avoided. Resulting rectal and rectocolonic strictures, rectovaginal fistulas, and shortening and stenosis of the vagina present very difficult problems that frequently require a colosto...
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Veröffentlicht in: | Am. J. Clin. Oncol.; (United States) 1984-02, Vol.7 (1), p.81-89 |
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description | Severe damage to the pelvic viscera is a complication of irradiation therapy that, unfortunately, cannot always be avoided. Resulting rectal and rectocolonic strictures, rectovaginal fistulas, and shortening and stenosis of the vagina present very difficult problems that frequently require a colostomy for relief and may permanently impair sexual function. The authors present a new approach to correction of these unfortunate lesions based on the use of proximal nonirradiated colon which serves as a vascular pedicle graft to correct the defect without a complicated and massive resection. Twenty-two such operations have been done with 19 satisfactory to excellent results and two total failures (one death from small bowel complications). All patterns and combinations of irradiation injury have been found amenable to this technique of repair. These have included both web and linear strictures with and without fistulas. In half of the patients, it was possible to make use of normal colon bypassed by a prior colostomy. Normal nonirradiated colon with good blood supply will heal satisfactorily to irradiated colon or rectum, thus making excision of all the irradiated tissue unnecessary. The results of this surgical approach have thus far been gratifying and warrant further trials for these distressing injuries. |
doi_str_mv | 10.1097/00000421-198402000-00011 |
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M ; JOHNSTON, W. D ; KRAYBILL, W. G ; LOPEZ, M. J</creator><creatorcontrib>BRICKER, E. M ; JOHNSTON, W. D ; KRAYBILL, W. G ; LOPEZ, M. J ; Washington Univ. of Medicine, St. Louis, MO</creatorcontrib><description>Severe damage to the pelvic viscera is a complication of irradiation therapy that, unfortunately, cannot always be avoided. Resulting rectal and rectocolonic strictures, rectovaginal fistulas, and shortening and stenosis of the vagina present very difficult problems that frequently require a colostomy for relief and may permanently impair sexual function. The authors present a new approach to correction of these unfortunate lesions based on the use of proximal nonirradiated colon which serves as a vascular pedicle graft to correct the defect without a complicated and massive resection. Twenty-two such operations have been done with 19 satisfactory to excellent results and two total failures (one death from small bowel complications). All patterns and combinations of irradiation injury have been found amenable to this technique of repair. These have included both web and linear strictures with and without fistulas. In half of the patients, it was possible to make use of normal colon bypassed by a prior colostomy. Normal nonirradiated colon with good blood supply will heal satisfactorily to irradiated colon or rectum, thus making excision of all the irradiated tissue unnecessary. The results of this surgical approach have thus far been gratifying and warrant further trials for these distressing injuries.</description><identifier>ISSN: 0277-3732</identifier><identifier>EISSN: 1537-453X</identifier><identifier>DOI: 10.1097/00000421-198402000-00011</identifier><identifier>PMID: 6695854</identifier><identifier>CODEN: AJCODI</identifier><language>eng</language><publisher>Hagerstown, MD: Lippincott Williams & Wilkins</publisher><subject>550603 - Medicine- External Radiation in Therapy- (1980-) ; 560151 - Radiation Effects on Animals- Man ; Biological and medical sciences ; BIOLOGICAL EFFECTS ; BIOLOGICAL RADIATION EFFECTS ; BODY ; BODY AREAS ; Colon - surgery ; Colon, Sigmoid - surgery ; Colostomy ; DIGESTIVE SYSTEM ; Female ; FEMALE GENITALS ; GASTROINTESTINAL TRACT ; GRAFTS ; Humans ; Hysterectomy ; INTESTINES ; LARGE INTESTINE ; Medical sciences ; MEDICINE ; NUCLEAR MEDICINE ; ORGANS ; PATIENTS ; PELVIS ; Pelvis - radiation effects ; POST-IRRADIATION THERAPY ; RADIATION EFFECTS ; Radiation Injuries - surgery ; RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT ; RADIOLOGY ; RADIOLOGY AND NUCLEAR MEDICINE ; RADIOTHERAPY ; Rectal Fistula - etiology ; Rectal Fistula - surgery ; SIDE EFFECTS ; SURGERY ; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases ; Surgery of the genital tract and mammary gland ; THERAPY ; TRANSPLANTS ; Uterine Cervical Neoplasms - radiotherapy ; Uterine Cervical Neoplasms - surgery ; Uterine Neoplasms - radiotherapy ; Vaginal Fistula - etiology ; Vaginal Fistula - surgery</subject><ispartof>Am. J. Clin. 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D</creatorcontrib><creatorcontrib>KRAYBILL, W. G</creatorcontrib><creatorcontrib>LOPEZ, M. J</creatorcontrib><creatorcontrib>Washington Univ. of Medicine, St. Louis, MO</creatorcontrib><title>Reconstructive surgery for the complications of pelvic irradiation</title><title>Am. J. Clin. Oncol.; (United States)</title><addtitle>Am J Clin Oncol</addtitle><description>Severe damage to the pelvic viscera is a complication of irradiation therapy that, unfortunately, cannot always be avoided. Resulting rectal and rectocolonic strictures, rectovaginal fistulas, and shortening and stenosis of the vagina present very difficult problems that frequently require a colostomy for relief and may permanently impair sexual function. The authors present a new approach to correction of these unfortunate lesions based on the use of proximal nonirradiated colon which serves as a vascular pedicle graft to correct the defect without a complicated and massive resection. Twenty-two such operations have been done with 19 satisfactory to excellent results and two total failures (one death from small bowel complications). All patterns and combinations of irradiation injury have been found amenable to this technique of repair. These have included both web and linear strictures with and without fistulas. In half of the patients, it was possible to make use of normal colon bypassed by a prior colostomy. Normal nonirradiated colon with good blood supply will heal satisfactorily to irradiated colon or rectum, thus making excision of all the irradiated tissue unnecessary. The results of this surgical approach have thus far been gratifying and warrant further trials for these distressing injuries.</description><subject>550603 - Medicine- External Radiation in Therapy- (1980-)</subject><subject>560151 - Radiation Effects on Animals- Man</subject><subject>Biological and medical sciences</subject><subject>BIOLOGICAL EFFECTS</subject><subject>BIOLOGICAL RADIATION EFFECTS</subject><subject>BODY</subject><subject>BODY AREAS</subject><subject>Colon - surgery</subject><subject>Colon, Sigmoid - surgery</subject><subject>Colostomy</subject><subject>DIGESTIVE SYSTEM</subject><subject>Female</subject><subject>FEMALE GENITALS</subject><subject>GASTROINTESTINAL TRACT</subject><subject>GRAFTS</subject><subject>Humans</subject><subject>Hysterectomy</subject><subject>INTESTINES</subject><subject>LARGE INTESTINE</subject><subject>Medical sciences</subject><subject>MEDICINE</subject><subject>NUCLEAR MEDICINE</subject><subject>ORGANS</subject><subject>PATIENTS</subject><subject>PELVIS</subject><subject>Pelvis - radiation effects</subject><subject>POST-IRRADIATION THERAPY</subject><subject>RADIATION EFFECTS</subject><subject>Radiation Injuries - surgery</subject><subject>RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT</subject><subject>RADIOLOGY</subject><subject>RADIOLOGY AND NUCLEAR MEDICINE</subject><subject>RADIOTHERAPY</subject><subject>Rectal Fistula - etiology</subject><subject>Rectal Fistula - surgery</subject><subject>SIDE EFFECTS</subject><subject>SURGERY</subject><subject>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</subject><subject>Surgery of the genital tract and mammary gland</subject><subject>THERAPY</subject><subject>TRANSPLANTS</subject><subject>Uterine Cervical Neoplasms - radiotherapy</subject><subject>Uterine Cervical Neoplasms - surgery</subject><subject>Uterine Neoplasms - radiotherapy</subject><subject>Vaginal Fistula - etiology</subject><subject>Vaginal Fistula - surgery</subject><issn>0277-3732</issn><issn>1537-453X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1984</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kF1LwzAUhoMoc05_ghDE2-pJ0jbJpQ6_YCCIgnehPU1dpFtLkg32780-XOAQcs7zHsJDCGVwx0DLe9ienLOMaZUDT48sFWMnZMwKIbO8EN-nZAxcykxIwc_JRQi_CSlKkCMyKktdqCIfk8cPi_0yRL_C6NaWhpX_sX5D297TOLcU-8XQOayiSxTtWzrYbu2QOu-rxu3al-Ssrbpgrw73hHw9P31OX7PZ-8vb9GGWoSjLmKmiYdA0WOeSgwKQoGQjtLLCatnkZQ2WSy0YqgKlbhJRK7Sg65a1nAkuJuRmv7cP0ZmALlqcp88vLUYjgQkhIUFqD6HvQ_C2NYN3i8pvDAOzVWf-1ZmjOrNTl6LX--iwqhe2OQYPrtL89jCvAlZd66slunDENC8F11L8AeDpdW8</recordid><startdate>198402</startdate><enddate>198402</enddate><creator>BRICKER, E. M</creator><creator>JOHNSTON, W. D</creator><creator>KRAYBILL, W. G</creator><creator>LOPEZ, M. J</creator><general>Lippincott Williams & Wilkins</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>OTOTI</scope></search><sort><creationdate>198402</creationdate><title>Reconstructive surgery for the complications of pelvic irradiation</title><author>BRICKER, E. M ; JOHNSTON, W. D ; KRAYBILL, W. G ; LOPEZ, M. J</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c366t-85d10ddcb47208007087d398e3e97d46b0e27931c85c79d800b8ce09bf1f21323</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1984</creationdate><topic>550603 - Medicine- External Radiation in Therapy- (1980-)</topic><topic>560151 - Radiation Effects on Animals- Man</topic><topic>Biological and medical sciences</topic><topic>BIOLOGICAL EFFECTS</topic><topic>BIOLOGICAL RADIATION EFFECTS</topic><topic>BODY</topic><topic>BODY AREAS</topic><topic>Colon - surgery</topic><topic>Colon, Sigmoid - surgery</topic><topic>Colostomy</topic><topic>DIGESTIVE SYSTEM</topic><topic>Female</topic><topic>FEMALE GENITALS</topic><topic>GASTROINTESTINAL TRACT</topic><topic>GRAFTS</topic><topic>Humans</topic><topic>Hysterectomy</topic><topic>INTESTINES</topic><topic>LARGE INTESTINE</topic><topic>Medical sciences</topic><topic>MEDICINE</topic><topic>NUCLEAR MEDICINE</topic><topic>ORGANS</topic><topic>PATIENTS</topic><topic>PELVIS</topic><topic>Pelvis - radiation effects</topic><topic>POST-IRRADIATION THERAPY</topic><topic>RADIATION EFFECTS</topic><topic>Radiation Injuries - surgery</topic><topic>RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT</topic><topic>RADIOLOGY</topic><topic>RADIOLOGY AND NUCLEAR MEDICINE</topic><topic>RADIOTHERAPY</topic><topic>Rectal Fistula - etiology</topic><topic>Rectal Fistula - surgery</topic><topic>SIDE EFFECTS</topic><topic>SURGERY</topic><topic>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</topic><topic>Surgery of the genital tract and mammary gland</topic><topic>THERAPY</topic><topic>TRANSPLANTS</topic><topic>Uterine Cervical Neoplasms - radiotherapy</topic><topic>Uterine Cervical Neoplasms - surgery</topic><topic>Uterine Neoplasms - radiotherapy</topic><topic>Vaginal Fistula - etiology</topic><topic>Vaginal Fistula - surgery</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>BRICKER, E. M</creatorcontrib><creatorcontrib>JOHNSTON, W. D</creatorcontrib><creatorcontrib>KRAYBILL, W. G</creatorcontrib><creatorcontrib>LOPEZ, M. J</creatorcontrib><creatorcontrib>Washington Univ. of Medicine, St. Louis, MO</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>OSTI.GOV</collection><jtitle>Am. J. Clin. Oncol.; (United States)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>BRICKER, E. M</au><au>JOHNSTON, W. D</au><au>KRAYBILL, W. G</au><au>LOPEZ, M. J</au><aucorp>Washington Univ. of Medicine, St. Louis, MO</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Reconstructive surgery for the complications of pelvic irradiation</atitle><jtitle>Am. J. Clin. Oncol.; (United States)</jtitle><addtitle>Am J Clin Oncol</addtitle><date>1984-02</date><risdate>1984</risdate><volume>7</volume><issue>1</issue><spage>81</spage><epage>89</epage><pages>81-89</pages><issn>0277-3732</issn><eissn>1537-453X</eissn><coden>AJCODI</coden><abstract>Severe damage to the pelvic viscera is a complication of irradiation therapy that, unfortunately, cannot always be avoided. Resulting rectal and rectocolonic strictures, rectovaginal fistulas, and shortening and stenosis of the vagina present very difficult problems that frequently require a colostomy for relief and may permanently impair sexual function. The authors present a new approach to correction of these unfortunate lesions based on the use of proximal nonirradiated colon which serves as a vascular pedicle graft to correct the defect without a complicated and massive resection. Twenty-two such operations have been done with 19 satisfactory to excellent results and two total failures (one death from small bowel complications). All patterns and combinations of irradiation injury have been found amenable to this technique of repair. These have included both web and linear strictures with and without fistulas. In half of the patients, it was possible to make use of normal colon bypassed by a prior colostomy. Normal nonirradiated colon with good blood supply will heal satisfactorily to irradiated colon or rectum, thus making excision of all the irradiated tissue unnecessary. The results of this surgical approach have thus far been gratifying and warrant further trials for these distressing injuries.</abstract><cop>Hagerstown, MD</cop><pub>Lippincott Williams & Wilkins</pub><pmid>6695854</pmid><doi>10.1097/00000421-198402000-00011</doi><tpages>9</tpages></addata></record> |
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subjects | 550603 - Medicine- External Radiation in Therapy- (1980-) 560151 - Radiation Effects on Animals- Man Biological and medical sciences BIOLOGICAL EFFECTS BIOLOGICAL RADIATION EFFECTS BODY BODY AREAS Colon - surgery Colon, Sigmoid - surgery Colostomy DIGESTIVE SYSTEM Female FEMALE GENITALS GASTROINTESTINAL TRACT GRAFTS Humans Hysterectomy INTESTINES LARGE INTESTINE Medical sciences MEDICINE NUCLEAR MEDICINE ORGANS PATIENTS PELVIS Pelvis - radiation effects POST-IRRADIATION THERAPY RADIATION EFFECTS Radiation Injuries - surgery RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT RADIOLOGY RADIOLOGY AND NUCLEAR MEDICINE RADIOTHERAPY Rectal Fistula - etiology Rectal Fistula - surgery SIDE EFFECTS SURGERY Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgery of the genital tract and mammary gland THERAPY TRANSPLANTS Uterine Cervical Neoplasms - radiotherapy Uterine Cervical Neoplasms - surgery Uterine Neoplasms - radiotherapy Vaginal Fistula - etiology Vaginal Fistula - surgery |
title | Reconstructive surgery for the complications of pelvic irradiation |
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