Reconstructive surgery for the complications of pelvic irradiation

Severe damage to the pelvic viscera is a complication of irradiation therapy that, unfortunately, cannot always be avoided. Resulting rectal and rectocolonic strictures, rectovaginal fistulas, and shortening and stenosis of the vagina present very difficult problems that frequently require a colosto...

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Veröffentlicht in:Am. J. Clin. Oncol.; (United States) 1984-02, Vol.7 (1), p.81-89
Hauptverfasser: BRICKER, E. M, JOHNSTON, W. D, KRAYBILL, W. G, LOPEZ, M. J
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JOHNSTON, W. D
KRAYBILL, W. G
LOPEZ, M. J
description Severe damage to the pelvic viscera is a complication of irradiation therapy that, unfortunately, cannot always be avoided. Resulting rectal and rectocolonic strictures, rectovaginal fistulas, and shortening and stenosis of the vagina present very difficult problems that frequently require a colostomy for relief and may permanently impair sexual function. The authors present a new approach to correction of these unfortunate lesions based on the use of proximal nonirradiated colon which serves as a vascular pedicle graft to correct the defect without a complicated and massive resection. Twenty-two such operations have been done with 19 satisfactory to excellent results and two total failures (one death from small bowel complications). All patterns and combinations of irradiation injury have been found amenable to this technique of repair. These have included both web and linear strictures with and without fistulas. In half of the patients, it was possible to make use of normal colon bypassed by a prior colostomy. Normal nonirradiated colon with good blood supply will heal satisfactorily to irradiated colon or rectum, thus making excision of all the irradiated tissue unnecessary. The results of this surgical approach have thus far been gratifying and warrant further trials for these distressing injuries.
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All patterns and combinations of irradiation injury have been found amenable to this technique of repair. These have included both web and linear strictures with and without fistulas. In half of the patients, it was possible to make use of normal colon bypassed by a prior colostomy. Normal nonirradiated colon with good blood supply will heal satisfactorily to irradiated colon or rectum, thus making excision of all the irradiated tissue unnecessary. 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D</creatorcontrib><creatorcontrib>KRAYBILL, W. G</creatorcontrib><creatorcontrib>LOPEZ, M. J</creatorcontrib><creatorcontrib>Washington Univ. of Medicine, St. Louis, MO</creatorcontrib><title>Reconstructive surgery for the complications of pelvic irradiation</title><title>Am. J. Clin. Oncol.; (United States)</title><addtitle>Am J Clin Oncol</addtitle><description>Severe damage to the pelvic viscera is a complication of irradiation therapy that, unfortunately, cannot always be avoided. Resulting rectal and rectocolonic strictures, rectovaginal fistulas, and shortening and stenosis of the vagina present very difficult problems that frequently require a colostomy for relief and may permanently impair sexual function. The authors present a new approach to correction of these unfortunate lesions based on the use of proximal nonirradiated colon which serves as a vascular pedicle graft to correct the defect without a complicated and massive resection. 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POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT</topic><topic>RADIOLOGY</topic><topic>RADIOLOGY AND NUCLEAR MEDICINE</topic><topic>RADIOTHERAPY</topic><topic>Rectal Fistula - etiology</topic><topic>Rectal Fistula - surgery</topic><topic>SIDE EFFECTS</topic><topic>SURGERY</topic><topic>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</topic><topic>Surgery of the genital tract and mammary gland</topic><topic>THERAPY</topic><topic>TRANSPLANTS</topic><topic>Uterine Cervical Neoplasms - radiotherapy</topic><topic>Uterine Cervical Neoplasms - surgery</topic><topic>Uterine Neoplasms - radiotherapy</topic><topic>Vaginal Fistula - etiology</topic><topic>Vaginal Fistula - surgery</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>BRICKER, E. M</creatorcontrib><creatorcontrib>JOHNSTON, W. D</creatorcontrib><creatorcontrib>KRAYBILL, W. G</creatorcontrib><creatorcontrib>LOPEZ, M. 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Oncol.; (United States)</jtitle><addtitle>Am J Clin Oncol</addtitle><date>1984-02</date><risdate>1984</risdate><volume>7</volume><issue>1</issue><spage>81</spage><epage>89</epage><pages>81-89</pages><issn>0277-3732</issn><eissn>1537-453X</eissn><coden>AJCODI</coden><abstract>Severe damage to the pelvic viscera is a complication of irradiation therapy that, unfortunately, cannot always be avoided. Resulting rectal and rectocolonic strictures, rectovaginal fistulas, and shortening and stenosis of the vagina present very difficult problems that frequently require a colostomy for relief and may permanently impair sexual function. The authors present a new approach to correction of these unfortunate lesions based on the use of proximal nonirradiated colon which serves as a vascular pedicle graft to correct the defect without a complicated and massive resection. Twenty-two such operations have been done with 19 satisfactory to excellent results and two total failures (one death from small bowel complications). All patterns and combinations of irradiation injury have been found amenable to this technique of repair. These have included both web and linear strictures with and without fistulas. In half of the patients, it was possible to make use of normal colon bypassed by a prior colostomy. Normal nonirradiated colon with good blood supply will heal satisfactorily to irradiated colon or rectum, thus making excision of all the irradiated tissue unnecessary. The results of this surgical approach have thus far been gratifying and warrant further trials for these distressing injuries.</abstract><cop>Hagerstown, MD</cop><pub>Lippincott Williams &amp; Wilkins</pub><pmid>6695854</pmid><doi>10.1097/00000421-198402000-00011</doi><tpages>9</tpages></addata></record>
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subjects 550603 - Medicine- External Radiation in Therapy- (1980-)
560151 - Radiation Effects on Animals- Man
Biological and medical sciences
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BODY
BODY AREAS
Colon - surgery
Colon, Sigmoid - surgery
Colostomy
DIGESTIVE SYSTEM
Female
FEMALE GENITALS
GASTROINTESTINAL TRACT
GRAFTS
Humans
Hysterectomy
INTESTINES
LARGE INTESTINE
Medical sciences
MEDICINE
NUCLEAR MEDICINE
ORGANS
PATIENTS
PELVIS
Pelvis - radiation effects
POST-IRRADIATION THERAPY
RADIATION EFFECTS
Radiation Injuries - surgery
RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT
RADIOLOGY
RADIOLOGY AND NUCLEAR MEDICINE
RADIOTHERAPY
Rectal Fistula - etiology
Rectal Fistula - surgery
SIDE EFFECTS
SURGERY
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Surgery of the genital tract and mammary gland
THERAPY
TRANSPLANTS
Uterine Cervical Neoplasms - radiotherapy
Uterine Cervical Neoplasms - surgery
Uterine Neoplasms - radiotherapy
Vaginal Fistula - etiology
Vaginal Fistula - surgery
title Reconstructive surgery for the complications of pelvic irradiation
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